Assessment of Structural Intolerance and Durability
General Structure Information 3pfn NADK crystal structure of human nad kinase 2.7Å AUTH H.WANG,W.TEMPEL,A.K.WERNIMONT,Y.TONG,X.GUAN,Y.SHEN,Y.LI,AUTH 2 C.H.ARROWSMITH,A.M.EDWARDS,C.BOUNTRA,J.WEIGELT,H.PARKTITL CRYSTAL STRUCTURE OF HUMAN NAD KINASEREF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped Variants
General Structure Information 3qve HBP1 crystal structure of human hmg box-containing protein 1, hbp1 2.04Å AUTH A.CHAIKUAD,E.KRYSZTOFINSKA,R.COCKING,M.VOLLMAR,W.W.YUE,AUTH 2 T.KROJER,E.UGOCHUKWU,P.FILIPPAKOPOULOS,F.VON DELFT,AUTH 3 C.H.ARROWSMITH,J.WEIGELT,A.M.EDWARDS,C.BOUNTRA,U.OPPERMANN,AUTH 4 STRUCTURAL GENOMICS CONSORTIUMTITL CRYSTAL STRUCTURE OF HUMAN HMG BOX-CONTAINING PROTEIN 1,TITL 2 HBP1REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2nzj REM1 the crystal structure of rem1 in complex with gdp 2.5Å AUTH A.P.TURNBULL,E.PAPAGRIGORIOU,E.UGOCHUKWU,J.M.ELKINS,AUTH 2 M.SOUNDARARAJAN,X.YANG,F.GORREC,C.UMEANO,E.SALAH,N.BURGESS,AUTH 3 C.JOHANSSON,G.BERRIDGE,O.GILEADI,J.BRAY,B.MARSDEN,S.WATTS,AUTH 4 F.VON DELFT,J.WEIGELT,A.EDWARDS,C.H.ARROWSMITH,M.SUNDSTROM,AUTH 5 D.DOYLETITL THE CRYSTAL STRUCTURE OF REM1 IN COMPLEX WITH GDPREF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped Variants
General Structure Information 3fm0 CIAO1 crystal structure of wd40 protein ciao1 1.7Å AUTH C.XU,J.MINTITL STRUCTURE AND FUNCTION OF WD40 DOMAIN PROTEINS.REF PROTEIN CELL V. 2 202 2011REFN ISSN 1674-800XPMID 21468892DOI 10.1007/S13238-011-1018-1 Variant Set Distributions Mapped Variants
General Structure Information 2a14 INMT crystal structure of human indolethylamine n- methyltransferase with sah 1.7Å AUTH H.WU,A.DONG,H.ZENG,P.LOPPNAU,M.SUNDSTROM,AUTH 2 C.H.ARROWSMITH,A.M.EDWARDS,A.BOCHKAREV,AUTH 3 A.N.PLOTNIKOVTITL THE CRYSTAL STRUCTURE OF HUMAN INDOLETHYLAMINETITL 2 N-METHYLTRANSFERASE IN COMPLEX WITH SAH.REF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped Variants
General Structure Information 2fne MPDZ the crystal structure of the 13th pdz domain of mpdz 1.83Å AUTH J.M.ELKINS,E.PAPAGRIGORIOU,G.BERRIDGE,X.YANG,AUTH 2 C.PHILLIPS,C.GILEADI,P.SAVITSKY,D.A.DOYLETITL STRUCTURE OF PICK1 AND OTHER PDZ DOMAINS OBTAINEDTITL 2 WITH THE HELP OF SELF-BINDING C-TERMINALTITL 3 EXTENSIONS.REF PROTEIN SCI. V. 16 683 2007REFN ISSN 0961-8368PMID 17384233DOI 10.1110/PS.062657507 Variant Set Distributions Mapped Variants
General Structure Information 3bpj EIF3J crystal structure of human translation initiation factor 3, subunit 1 alpha 1.85Å AUTH L.NEDYALKOVA,B.HONG,W.TEMPEL,F.MACKENZIE,C.H.ARROWSMITH,AUTH 2 A.M.EDWARDS,J.WEIGELT,A.BOCHKAREV,H.PARKTITL CRYSTAL STRUCTURE OF HUMAN TRANSLATION INITIATION FACTOR 3,TITL 2 SUBUNIT 1 ALPHA.REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 3q3j PLXNA2 crystal structure of plexin a2 rbd in complex with rnd1 1.97Å AUTH H.WANG,W.TEMPEL,Y.TONG,X.GUAN,L.SHEN,L.BUREN,N.ZHANG,AUTH 2 A.K.WERNIMONT,L.CROMBET,C.H.ARROWSMITH,A.M.EDWARDS,AUTH 3 C.BOUNTRA,J.WEIGELT,H.PARKTITL CRYSTAL STRUCTURE OF PLEXIN A2 RBD IN COMPLEX WITH RND1REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2gf0 DIRAS1 the crystal structure of the human diras1 gtpase in the inactive gdp bound state 1.9Å AUTH A.P.TURNBULL,E.PAPAGRIGORIOU,X.YANG,G.SCHOCH,AUTH 2 J.ELKINS,O.GILEADI,E.SALAH,J.BRAY,L.WEN-HWA,AUTH 3 O.FEDOROV,F.E.NIESEN,F.VON DELFT,J.WEIGELT,AUTH 4 A.EDWARDS,C.ARROWSMITH,M.SUNDSTROM,D.DOYLETITL THE CRYSTAL STRUCTURE OF THE HUMAN DIRAS1 GTPASETITL 2 IN THE INACTIVE GDP BOUND STATEREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 3kuz PLXNC1 crystal structure of the ubiquitin like domain of plxnc1 2.3Å AUTH H.WANG,B.LI,W.TEMPEL,Y.TONG,X.GUAN,N.ZHONG,AUTH 2 L.CROMBET,F.MACKENZIE,M.BUCK,C.H.ARROWSMITH,AUTH 3 A.M.EDWARDS,C.BOUNTRA,J.WEIGELT,A.BOCHKAREV,H.PARKTITL CRYSTAL STRUCTURE OF THE UBIQUITIN LIKE DOMAIN OFTITL 2 PLXNC1REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants