General Structure Information
| PDB ID | 2nzj |
| HGNC Gene Label(s) | REM1 |
| Structure Name | the crystal structure of rem1 in complex with gdp |
| Resolution | 2.5Å |
| Reference | AUTH A.P.TURNBULL,E.PAPAGRIGORIOU,E.UGOCHUKWU,J.M.ELKINS,AUTH 2 M.SOUNDARARAJAN,X.YANG,F.GORREC,C.UMEANO,E.SALAH,N.BURGESS,AUTH 3 C.JOHANSSON,G.BERRIDGE,O.GILEADI,J.BRAY,B.MARSDEN,S.WATTS,AUTH 4 F.VON DELFT,J.WEIGELT,A.EDWARDS,C.H.ARROWSMITH,M.SUNDSTROM,AUTH 5 D.DOYLETITL THE CRYSTAL STRUCTURE OF REM1 IN COMPLEX WITH GDPREF TO BE PUBLISHEDREFN |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 158 |
| Number Of SNVs | 47 |
| Number Of Permutations | 4437 |
| Optimal Distance Threshold | 12.0 |
| K Statistic | 0.205 |
| p-value | 0.158 |
COSMIC
| Number Of Residues | 158 |
| Number Of SNVs | 3 |
| Number Of Permutations | 190 |
| Optimal Distance Threshold | 40.0 |
| K Statistic | 0.667 |
| p-value | 0.014 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 47 |
| Number Of COSMIC SNVs | 3 |
| Optimal Distance Threshold | 22.0 |
| K Statistic | -0.673 |
| p-value | 0.021 |