General Structure Information 3evs GDF5 crystal structure of the gdf-5:bmp receptor ib complex. 2.1Å AUTH A.KOTZSCH,J.NICKEL,A.SEHER,W.SEBALD,T.D.MULLERTITL CRYSTAL STRUCTURE ANALYSIS REVEALS A SPRING-LOADED LATCH ASTITL 2 MOLECULAR MECHANISM FOR GDF-5-TYPE I RECEPTOR SPECIFICITY.REF EMBO J. V. 28 937 2009REFN ISSN 0261-4189PMID 19229295DOI 10.1038/EMBOJ.2009.37 Variant Set Distributions Pathogenic Proximity Analysis Mapped Variants
General Structure Information 3c59 GLP1R crystal structure of the ligand-bound glucagon-like peptide-1 receptor extracellular domain 2.3Å AUTH S.RUNGE,H.THOGERSEN,K.MADSEN,J.LAU,R.RUDOLPHTITL CRYSTAL STRUCTURE OF THE LIGAND-BOUND GLUCAGON-LIKETITL 2 PEPTIDE-1 RECEPTOR EXTRACELLULAR DOMAINREF J.BIOL.CHEM. V. 283 11340 2008REFN ISSN 0021-9258PMID 18287102DOI 10.1074/JBC.M708740200 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 2w86 FBN1 crystal structure of fibrillin-1 domains cbegf9hyb2cbegf10, calcium saturated form 1.8Å AUTH S.A.JENSEN,S.IQBAL,E.D.LOWE,C.REDFIELD,P.A.HANDFORDTITL STRUCTURE AND INTERDOMAIN INTERACTIONS OF A HYBRIDTITL 2 DOMAIN: A DISULPHIDE-RICH MODULE OF THETITL 3 FIBRILLIN/LTBP SUPERFAMILY OF MATRIX PROTEINS.REF STRUCTURE V. 17 759 2009REFN ISSN 0969-2126PMID 19446531DOI 10.1016/J.STR.2009.03.014 Variant Set Distributions Pathogenic Proximity Analysis Mapped Variants
General Structure Information 3g81 SFTPD crystal structure of the trimeric neck and carbohydrate recognition domain of human surfactant protein d in complex with alpha methyl mannoside 1.8Å AUTH E.CROUCH,K.HARTSHORN,T.HORLACHER,B.MCDONALD,K.SMITH,AUTH 2 T.CAFARELLA,B.SEATON,P.H.SEEBERGER,J.HEADTITL RECOGNITION OF MANNOSYLATED LIGANDS AND INFLUENZA A VIRUS BYTITL 2 HUMAN SURFACTANT PROTEIN D: CONTRIBUTIONS OF AN EXTENDEDTITL 3 SITE AND RESIDUE 343.REF BIOCHEMISTRY […]
General Structure Information 3e0g LIFR structure of the leukemia inhibitory factor receptor (lif-r) domains d1-d5 3.1Å AUTH G.SKINIOTIS,P.J.LUPARDUS,M.MARTICK,T.WALZ,K.C.GARCIATITL STRUCTURAL ORGANIZATION OF A FULL-LENGTH GP130/LIF-RTITL 2 CYTOKINE RECEPTOR TRANSMEMBRANE COMPLEX.REF MOL.CELL V. 31 737 2008REFN ISSN 1097-2765PMID 18775332DOI 10.1016/J.MOLCEL.2008.08.011 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped Variants
General Structure Information 3l5w IL13 crystal structure of the complex between il-13 and c836 fab 2.0Å AUTH J.FRANSSON,A.TEPLYAKOV,G.RAGHUNATHAN,E.CHI,W.CORDIER,AUTH 2 T.DINH,Y.FENG,J.GILES-KOMAR,G.GILLILAND,B.LOLLO,T.J.MALIA,AUTH 3 W.NISHIOKA,G.OBMOLOVA,S.ZHAO,Y.ZHAO,R.V.SWANSON,J.C.ALMAGROTITL HUMAN FRAMEWORK ADAPTATION OF A MOUSE ANTI-HUMAN IL-13TITL 2 ANTIBODY.REF J.MOL.BIOL. V. 398 214 2010REFN ISSN 0022-2836PMID 20226193DOI 10.1016/J.JMB.2010.03.004 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped […]
General Structure Information 3cki TIMP3 crystal structure of the tace-n-timp-3 complex 2.3Å AUTH M.WISNIEWSKA,P.GOETTIG,K.MASKOS,E.BELOUSKI,AUTH 2 D.WINTERS,R.HECHT,R.BLACK,W.BODETITL STRUCTURAL DETERMINANTS OF THE ADAM INHIBITION BYTITL 2 TIMP-3: CRYSTAL STRUCTURE OF THE TACE-N-TIMP-3TITL 3 COMPLEX.REF J.MOL.BIOL. V. 381 1307 2008REFN ISSN 0022-2836PMID 18638486DOI 10.1016/J.JMB.2008.06.088 Variant Set Distributions Mapped Variants
General Structure Information 3l5h IL6ST crystal structure of the full ectodomain of human gp130: new insights into the molecular assembly of receptor complexes 3.6Å AUTH Y.XU,N.KERSHAW,C.S.LUO,P.SOO,M.POCOCK,P.E.CZABOTAR,AUTH 2 D.J.HILTON,N.A.NICOLA,T.P.J.GARRETT,J.G.ZHANGTITL CRYSTAL STRUCTURE OF THE ENTIRE ECTODOMAIN OF GP130:TITL 2 INSIGHTS INTO THE MOLECULAR ASSEMBLY OF THE TALL CYTOKINETITL 3 RECEPTOR COMPLEXESREF TO BE PUBLISHEDREFN Variant Set Distributions […]
General Structure Information 3eyc LCN1 new crystal structure of human tear lipocalin in complex with 1,4-butanediol in space group p21 2.6Å AUTH D.A.BREUSTEDT,L.CHATWELL,A.SKERRATITL A NEW CRYSTAL FORM OF HUMAN TEAR LIPOCALIN REVEALSTITL 2 HIGH FLEXIBILITY IN THE LOOP REGION AND INDUCED FITTITL 3 IN THE LIGAND CAVITYREF ACTA CRYSTALLOGR.,SECT.D V. 65 1118 2009REFN ISSN 0907-4449PMID […]
General Structure Information 2v5e GDNF the structure of the gdnf:coreceptor complex: insights into ret signalling and heparin binding. 2.35Å AUTH V.PARKASH,V.-M.LEPPANEN,H.VIRTANEN,J.-M.JURVANSUU,AUTH 2 M.M.BESPALOV,Y.A.SIDOROVA,P.RUNEBERG-ROOS,M.SAARMA,AUTH 3 A.GOLDMANTITL THE STRUCTURE OF THE GLIAL CELL LINE-DERIVEDTITL 2 NEUROTROPHIC FACTOR-CORECEPTOR COMPLEX: INSIGHTSTITL 3 INTO RET SIGNALING AND HEPARIN BINDING.REF J.BIOL.CHEM. V. 283 35164 2008REFN ISSN 0021-9258PMID 18845535DOI 10.1074/JBC.M802543200 Variant Set […]