Assessment of Structural Intolerance and Durability
General Structure Information 3b4v FSTL3 x-ray structure of activin in complex with fstl3 2.48Å AUTH R.STAMLER,H.T.KEUTMANN,Y.SIDIS,C.KATTAMURI,A.SCHNEYER,AUTH 2 T.B.THOMPSONTITL THE STRUCTURE OF FSTL3.ACTIVIN A COMPLEX. DIFFERENTIALTITL 2 BINDING OF N-TERMINAL DOMAINS INFLUENCES FOLLISTATIN-TYPETITL 3 ANTAGONIST SPECIFICITY.REF J.BIOL.CHEM. V. 283 32831 2008REFN ISSN 0021-9258PMID 18768470DOI 10.1074/JBC.M801266200 Variant Set Distributions Mapped Variants
General Structure Information 2wfh SLIT2 the human slit 2 dimerization domain d4 1.8Å AUTH E.SEIRADAKE,A.C.VON PHILIPSBORN,M.HENRY,M.FRITZ,AUTH 2 H.LORTAT-JACOB,M.JAMIN,W.HEMRIKA,M.BASTMEYER,S.CUSACK,AUTH 3 A.A.MCCARTHYTITL STRUCTURE AND FUNCTIONAL RELEVANCE OF THE SLIT2TITL 2 HOMODIMERIZATION DOMAIN.REF EMBO REP. V. 10 736 2009REFN ISSN 1469-221XPMID 19498462DOI 10.1038/EMBOR.2009.95 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 2qqm NRP1 crystal structure of the a2b1b2 domains from human neuropilin-1 2.0Å AUTH B.A.APPLETON,P.WU,J.MALONEY,J.YIN,W.C.LIANG,S.STAWICKI,AUTH 2 K.MORTARA,K.K.BOWMAN,J.M.ELLIOTT,W.DESMARAIS,J.F.BAZAN,AUTH 3 A.BAGRI,M.TESSIER-LAVIGNE,A.W.KOCH,Y.WU,R.J.WATTS,C.WIESMANNTITL STRUCTURAL STUDIES OF NEUROPILIN/ANTIBODY COMPLEXES PROVIDETITL 2 INSIGHTS INTO SEMAPHORIN AND VEGF BINDINGREF EMBO J. V. 26 4902 2007REFN ISSN 0261-4189PMID 17989695DOI 10.1038/SJ.EMBOJ.7601906 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic […]
General Structure Information 2zhk LGALS9 crystal structure of human galectin-9 n-terminal crd in complex with n-acetyllactosamine dimer (crystal 1) 1.8Å AUTH M.NAGAE,N.NISHI,T.MURATA,T.USUI,T.NAKAMURA,S.WAKATSUKI,AUTH 2 R.KATOTITL STRUCTURAL ANALYSIS OF THE RECOGNITION MECHANISM OFTITL 2 POLY-N-ACETYLLACTOSAMINE BY THE HUMAN GALECTIN-9 N-TERMINALTITL 3 CARBOHYDRATE RECOGNITION DOMAIN.REF GLYCOBIOLOGY V. 19 112 2009REFN ISSN 0959-6658PMID 18977853DOI 10.1093/GLYCOB/CWN121 Variant Set Distributions Mapped […]
General Structure Information 3llk QSOX1 sulfhydryl oxidase fragment of human qsox1 2.0Å AUTH A.ALON,E.J.HECKLER,C.THORPE,D.FASSTITL QSOX CONTAINS A PSEUDO-DIMER OF FUNCTIONAL AND DEGENERATETITL 2 SULFHYDRYL OXIDASE DOMAINS.REF FEBS LETT. V. 584 1521 2010REFN ISSN 0014-5793PMID 20211621DOI 10.1016/J.FEBSLET.2010.03.001 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 2wfq DHH crystal structure of the n-terminal signalling domain of human dhh without calcium 1.85Å AUTH B.BISHOP,A.R.ARICESCU,K.HARLOS,C.A.OCALLAGHAN,E.Y.JONES,AUTH 2 C.SIEBOLDTITL STRUCTURAL INSIGHTS INTO HEDGEHOG LIGAND SEQUESTRATION BYTITL 2 THE HUMAN HEDGEHOG-INTERACTING PROTEIN HIPREF NAT.STRUCT.MOL.BIOL. V. 16 698 2009REFN ISSN 1545-9993PMID 19561611DOI 10.1038/NSMB.1607 Variant Set Distributions Mapped Variants