General Structure Information
| PDB ID | 3l5w |
| HGNC Gene Label(s) | IL13 |
| Structure Name | crystal structure of the complex between il-13 and c836 fab |
| Resolution | 2.0Å |
| Reference | AUTH J.FRANSSON,A.TEPLYAKOV,G.RAGHUNATHAN,E.CHI,W.CORDIER,AUTH 2 T.DINH,Y.FENG,J.GILES-KOMAR,G.GILLILAND,B.LOLLO,T.J.MALIA,AUTH 3 W.NISHIOKA,G.OBMOLOVA,S.ZHAO,Y.ZHAO,R.V.SWANSON,J.C.ALMAGROTITL HUMAN FRAMEWORK ADAPTATION OF A MOUSE ANTI-HUMAN IL-13TITL 2 ANTIBODY.REF J.MOL.BIOL. V. 398 214 2010REFN ISSN 0022-2836PMID 20226193DOI 10.1016/J.JMB.2010.03.004 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 86 |
| Number Of SNVs | 20 |
| Number Of Permutations | 818 |
| Optimal Distance Threshold | 10.0 |
| K Statistic | 0.116 |
| p-value | 0.077 |
COSMIC
| Number Of Residues | 86 |
| Number Of SNVs | 3 |
| Number Of Permutations | 18 |
| Optimal Distance Threshold | 7.0 |
| K Statistic | 0.333 |
| p-value | 0.43 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 20 |
| Number Of COSMIC SNVs | 3 |
| Optimal Distance Threshold | 7.0 |
| K Statistic | 0.286 |
| p-value | 0.57 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
