Assessment of Structural Intolerance and Durability
General Structure Information 1x2p PRMT2 solution structure of the sh3 domain of the protein arginine n-methyltransferase 2 -1.0Å AUTH E.CHIKAYAMA,T.KIGAWA,K.SAITO,S.KOSHIBA,M.INOUE,AUTH 2 S.YOKOYAMATITL SOLUTION STRUCTURE OF THE SH3 DOMAIN OF THETITL 2 PROTEIN ARGININE N-METHYLTRANSFERASE 2REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 1×44 MYBPC1 solution structure of the third ig-like domain of myosin- dinding protein c, slow-type -1.0Å AUTH X.-R.QIN,C.KUROSAKI,F.HAYASHI,M.YOSHIDA,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE THIRD IG-LIKE DOMAIN OFTITL 2 MYOSIN-DINDING PROTEIN C, SLOW-TYPEREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2djn DLX5 the solution structure of the homeobox domain of human homeobox protein dlx-5 -1.0Å AUTH A.SASAGAWA,S.OHNISHI,N.TOCHIO,K.SAITO,S.KOSHIBA,AUTH 2 M.INOUE,T.KIGAWA,S.YOKOYAMATITL THE SOLUTION STRUCTURE OF THE HOMEOBOX DOMAIN OFTITL 2 HUMAN HOMEOBOX PROTEIN DLX-5REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2dav MYBPC1 solution structure of the first ig-like domain of myosin- binding protein c, slow-type -1.0Å AUTH X.R.QIN,T.NAGASHIMA,F.HAYASHI,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE FIRST IG-LIKE DOMAIN OFTITL 2 MYOSIN-BINDING PROTEIN C, SLOW-TYPEREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 1u7f SMAD3 crystal structure of the phosphorylated smad3/smad4 heterotrimeric complex 2.6Å AUTH B.M.CHACKO,B.Y.QIN,A.TIWARI,G.SHI,S.LAM,AUTH 2 L.J.HAYWARD,M.DE CAESTECKER,K.LINTITL STRUCTURAL BASIS OF HETEROMERIC SMAD PROTEINTITL 2 ASSEMBLY IN TGF-BETA SIGNALINGREF MOL.CELL V. 15 813 2004REFN ISSN 1097-2765PMID 15350224DOI 10.1016/J.MOLCEL.2004.07.016 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 2ctm HDLBP solution structure of the 14th kh type i domain from human vigilin -1.0Å AUTH T.TOMIZAWA,T.KIGAWA,S.KOSHIBA,M.INOUE,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE 14TH KH TYPE I DOMAINTITL 2 FROM HUMAN VIGILINREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 1foe RAC1 crystal structure of rac1 in complex with the guanine nucleotide exchange region of tiam1 2.8Å AUTH D.K.WORTHYLAKE,K.L.ROSSMAN,J.SONDEKTITL CRYSTAL STRUCTURE OF RAC1 IN COMPLEX WITH THETITL 2 GUANINE NUCLEOTIDE EXCHANGE REGION OF TIAM1.REF NATURE V. 408 682 2000REFN ISSN 0028-0836PMID 11130063DOI 10.1038/35047014 Variant Set Distributions Ripley’s K Analysis Plots Variant Set […]
General Structure Information 2gzd RAB11A crystal structure of rab11 in complex with rab11-fip2 2.44Å AUTH W.N.JAGOE,A.J.LINDSAY,R.J.READ,A.J.MCCOY,AUTH 2 M.W.MCCAFFREY,A.R.KHANTITL CRYSTAL STRUCTURE OF RAB11 IN COMPLEX WITH RAB11TITL 2 FAMILY INTERACTING PROTEIN 2.REF STRUCTURE V. 14 1273 2006REFN ISSN 0969-2126PMID 16905101DOI 10.1016/J.STR.2006.06.010 Variant Set Distributions Mapped Variants
General Structure Information 2xns GNAI1 crystal structure of human g alpha i1 bound to a designed helical peptide derived from the goloco motif of rgs14 3.41Å AUTH D.W.SAMMOND,D.E.BOSCH,G.L.BUTTERFOSS,C.PURBECK,AUTH 2 M.MACHIUS,D.P.SIDEROVSKI,B.KUHLMANTITL COMPUTATIONAL DESIGN OF THE SEQUENCE AND STRUCTURETITL 2 OF A PROTEIN-BINDING PEPTIDE.REF J.AM.CHEM.SOC. V. 133 4190 2011REFN ISSN 0002-7863PMID 21388199DOI 10.1021/JA110296Z Variant Set Distributions Ripley’s […]
General Structure Information 3ajb PEX3 crystal structure of human pex3p in complex with n-terminal pex19p peptide 2.5Å AUTH Y.SATO,H.SHIBATA,T.NAKATSU,H.NAKANO,Y.KASHIWAYAMA,T.IMANAKA,AUTH 2 H.KATOTITL STRUCTURAL BASIS FOR DOCKING OF PEROXISOMAL MEMBRANE PROTEINTITL 2 CARRIER PEX19P ONTO ITS RECEPTOR PEX3PREF EMBO J. V. 29 4083 2010REFN ISSN 0261-4189PMID 21102411DOI 10.1038/EMBOJ.2010.293 Variant Set Distributions Mapped Variants