General Structure Information
| PDB ID | 1foe |
| HGNC Gene Label(s) | RAC1 |
| Structure Name | crystal structure of rac1 in complex with the guanine nucleotide exchange region of tiam1 |
| Resolution | 2.8Å |
| Reference | AUTH D.K.WORTHYLAKE,K.L.ROSSMAN,J.SONDEKTITL CRYSTAL STRUCTURE OF RAC1 IN COMPLEX WITH THETITL 2 GUANINE NUCLEOTIDE EXCHANGE REGION OF TIAM1.REF NATURE V. 408 682 2000REFN ISSN 0028-0836PMID 11130063DOI 10.1038/35047014 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 177 |
| Number Of SNVs | 6 |
| Number Of Permutations | 596 |
| Optimal Distance Threshold | 9.0 |
| K Statistic | 0.2 |
| p-value | 0.447 |
COSMIC
| Number Of Residues | 177 |
| Number Of SNVs | 3 |
| Number Of Permutations | 46 |
| Optimal Distance Threshold | 8.0 |
| K Statistic | 0.333 |
| p-value | 0.346 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
