Assessment of Structural Intolerance and Durability
General Structure Information 3pfs BRPF3 pwwp domain of human bromodomain and phd finger-containing protein 3 1.9Å AUTH H.WU,H.ZENG,R.LAM,W.TEMPEL,M.F.AMAYA,C.XU,L.DOMBROVSKI,AUTH 2 W.QIU,Y.WANG,J.MINTITL STRUCTURAL AND HISTONE BINDING ABILITY CHARACTERIZATIONS OFTITL 2 HUMAN PWWP DOMAINS.REF PLOS ONE V. 6 18919 2011REFN ESSN 1932-6203PMID 21720545DOI 10.1371/JOURNAL.PONE.0018919 Variant Set Distributions Mapped Variants
General Structure Information 2xmq NDRG2 crystal structure of human ndrg2 protein provides insight into its role as a tumor suppressor 2.81Å AUTH J.HWANG,Y.KIM,H.B.KANG,L.JAROSZEWSKI,A.DEACON,AUTH 2 H.LEE,W.C.CHOI,K.J.KIM,C.H.KIM,B.S.KANG,J.O.LEE,AUTH 3 T.K.OH,J.W.KIM,I.A.WILSON,M.H.KIMTITL CRYSTAL STRUCTURE OF HUMAN NDRG2 PROTEIN PROVIDESTITL 2 INSIGHT INTO ITS ROLE AS A TUMOR SUPPRESSOR.REF J.BIOL.CHEM. V. 286 12450 2011REFN ISSN 0021-9258PMID 21247902DOI 10.1074/JBC.M110.170803 Variant Set Distributions […]
General Structure Information 1wjp ZBTB21 solution structure of zf-c2h2 domains from human zinc finger protein 295 -1.0Å AUTH T.TOMIZAWA,T.KIGAWA,K.SAITO,S.KOSHIBA,M.INOUE,AUTH 2 S.YOKOYAMATITL SOLUTION STRUCTURE OF ZF-C2H2 DOMAINS FROM HUMANTITL 2 ZINC FINGER PROTEIN 295REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 1mhq GGA2 crystal structure of human gga2 vhs domain 2.2Å AUTH G.ZHU,X.HE,S.TERZYAN,P.ZHAI,J.TANG,X.C.ZHANGTITL CRYSTAL STRUCTURE OF GGA2 VHS DOMAIN AND ITSTITL 2 IMPLICATION IN PLASTICITY IN THE LIGAND BINDINGTITL 3 POCKETREF FEBS LETT. V. 537 171 2003REFN ISSN 0014-5793PMID 12606052DOI 10.1016/S0014-5793(03)00095-4 Variant Set Distributions Mapped Variants
General Structure Information 2daw RWDD2A solution structure of the rwd domain of human rwd omain containing protein 2 -1.0Å AUTH M.YONEYAMA,T.KIGAWA,M.SATO,N.TOCHIO,S.KOSHIBA,AUTH 2 M.INOUE,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE RWD DOMAIN OF HUMAN RWDTITL 2 OMAIN CONTAINING PROTEIN 2REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2dzm FAF1 solution structure of the ubiquitin-like domain in human fas-associated factor 1 (hfaf1) -1.0Å AUTH C.ZHAO,M.SATO,S.KOSHIBA,S.WATANABE,T.HARADA,AUTH 2 T.KIGAWA,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE UBIQUITIN-LIKE DOMAIN INTITL 2 HUMAN FAS-ASSOCIATED FACTOR 1 (HFAF1)REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2ec1 NUP50 solution structure of the ranbd1 domain from human nucleoporin 50 kda -1.0Å AUTH H.P.ZHANG,C.KUROSAKI,M.YOSHIDA,F.HAYASHI,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE RANBD1 DOMAIN FROM HUMANTITL 2 NUCLEOPORIN 50 KDAREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 1wi1 CADPS solution structure of the ph domain of human calcium- dependent activator protein for secretion (caps) -1.0Å AUTH M.YONEYAMA,K.IZUMI,M.YOSHIDA,N.TOCHIO,S.KOSHIBA,AUTH 2 M.INOUE,T.KIGAWA,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE PH DOMAIN OF HUMANTITL 2 CALCIUM-DEPENDENT ACTIVATOR PROTEIN FOR SECRETIONTITL 3 (CAPS)REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 4f9b DBF4 human cdc7 kinase in complex with dbf4 and pha767491 2.5Å AUTH S.HUGHES,F.ELUSTONDO,A.DI FONZO,F.G.LEROUX,A.C.WONG,AUTH 2 A.P.SNIJDERS,S.J.MATTHEWS,P.CHEREPANOVTITL CRYSTAL STRUCTURE OF HUMAN CDC7 KINASE IN COMPLEX WITH ITSTITL 2 ACTIVATOR DBF4.REF NAT.STRUCT.MOL.BIOL. V. 19 1101 2012REFN ISSN 1545-9993PMID 23064647DOI 10.1038/NSMB.2404 Variant Set Distributions Mapped Variants
General Structure Information 3in5 POLK structure of human dna polymerase kappa inserting datp opposite an 8-oxog dna lesion 3.2Å AUTH R.VASQUEZ-DEL CARPIO,T.D.SILVERSTEIN,S.LONE,AUTH 2 M.K.SWAN,J.R.CHOUDHURY,R.E.JOHNSON,S.PRAKASH,AUTH 3 L.PRAKASH,A.K.AGGARWALTITL STRUCTURE OF HUMAN DNA POLYMERASE KAPPA INSERTINGTITL 2 DATP OPPOSITE AN 8-OXOG DNA LESIONREF PLOS ONE V. 4 E5766 2009REFN ESSN 1932-6203PMID 19492058DOI 10.1371/JOURNAL.PONE.0005766 Variant Set Distributions Pathogenic Proximity […]