3PFS.B | BRPF3

PDB ID	3pfs
HGNC Gene Label(s)	BRPF3
Structure Name	pwwp domain of human bromodomain and phd finger-containing protein 3
Resolution	1.9Å
Reference	AUTH H.WU,H.ZENG,R.LAM,W.TEMPEL,M.F.AMAYA,C.XU,L.DOMBROVSKI,AUTH 2 W.QIU,Y.WANG,J.MINTITL STRUCTURAL AND HISTONE BINDING ABILITY CHARACTERIZATIONS OFTITL 2 HUMAN PWWP DOMAINS.REF PLOS ONE V. 6 18919 2011REFN ESSN 1932-6203PMID 21720545DOI 10.1371/JOURNAL.PONE.0018919

ExAC Variants

Position	Variant	AA Change	PDB Chain Position	Structure Coordinates
6:36193050		S>N	B:1063	(34.75, -38.49, -21.18)
6:36193062	COSM3626171	P>L	B:1067	(25.06, -31.59, -18.21)
6:36193073	rs201220361	R>C	B:1071	(19.38, -33.31, -17.05)
6:36193074	rs370467092	R>H	B:1071	(19.38, -33.31, -17.05)
6:36193076	rs140562388	G>R	B:1072	(20.28, -37.47, -14.91)
6:36193077		G>E	B:1072	(20.28, -37.47, -14.91)
6:36193085	rs142171063	E>K	B:1075	(25.00, -44.90, -12.95)
6:36193087		E>D	B:1075	(25.00, -44.90, -12.95)
6:36196679		I>V	B:1094	(25.69, -43.75, -6.00)
6:36196685		D>N	B:1096	(23.12, -51.23, -6.99)
6:36196696		M>I	B:1099	(25.74, -54.65, -4.53)
6:36196697		P>S	B:1100	(27.09, -57.90, -5.45)
6:36196700	COSM3674693	R>W	B:1101	(24.71, -58.89, -0.45)
6:36196701		R>Q	B:1101	(24.71, -58.89, -0.45)
6:36196719		N>S	B:1107	(40.46, -48.75, -7.13)
6:36196742		P>A	B:1115	(22.21, -53.21, 5.05)
6:36196745		L>M	B:1116	(18.86, -56.88, 4.51)
6:36198217		R>K	B:1150	(19.02, -36.47, -9.11)
6:36198219		D>N	B:1151	(16.69, -33.00, -5.51)
6:36198252		V>M	B:1162	(31.63, -27.15, -7.53)
6:36198279		R>C	B:1171	(28.89, -20.06, 7.65)
6:36198280	COSM3873508	R>H	B:1171	(28.89, -20.06, 7.65)
6:36198294		R>C	B:1176	(34.38, -25.06, 6.53)
6:36198303	COSM483992	V>L	B:1179	(33.78, -32.01, 4.39)
6:36198316		Y>C	B:1183	(37.01, -34.08, -1.75)
6:36198322		R>H	B:1185	(37.97, -40.89, 3.48)
6:36198334		H>P	B:1189	(36.51, -44.26, -5.32)

3PFS.B | BRPF3.