Assessment of Structural Intolerance and Durability
General Structure Information 2ed1 ASAP1 solution structure of the sh3 domain of 130 kda phosphatidylinositol 4,5-biphosphate-dependent arf1 gtpase- activating protein -1.0Å AUTH H.ABE,N.TOCHIO,K.MIYAMOTO,K.SAITO,T.KIGAWA,AUTH 2 S.YOKOYAMATITL SOLUTION STRUCTURE OF THE SH3 DOMAIN OF 130 KDATITL 2 PHOSPHATIDYLINOSITOL 4,5-BIPHOSPHATE-DEPENDENTTITL 3 ARF1 GTPASE-ACTIVATING PROTEINREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2wfd LARS structure of the human cytosolic leucyl-trna synthetase editing domain 3.25Å AUTH E.SEIRADAKE,W.MAO,V.HERNANDEZ,S.J.BAKER,AUTH 2 J.J.PLATTNER,M.R.K.ALLEY,S.CUSACKTITL CRYSTAL STRUCTURES OF THE HUMAN AND FUNGALTITL 2 CYTOSOLIC LEUCYL-TRNA SYNTHETASE EDITING DOMAINS:TITL 3 A STRUCTURAL BASIS FOR THE RATIONAL DESIGN OFTITL 4 ANTIFUNGAL BENZOXABOROLES.REF J.MOL.BIOL. V. 390 196 2009REFN ISSN 0022-2836PMID 19426743DOI 10.1016/J.JMB.2009.04.073 Variant Set […]
General Structure Information 1t3g IL1RAPL1 crystal structure of the toll/interleukin-1 receptor (tir) domain of human il-1rapl 2.3Å AUTH J.A.KHAN,E.K.BRINT,L.A.J.ONEILL,L.TONGTITL CRYSTAL STRUCTURE OF THE TOLL/INTERLEUKIN-1TITL 2 RECEPTOR DOMAIN OF HUMAN IL-1RAPLREF J.BIOL.CHEM. V. 279 31664 2004REFN ISSN 0021-9258PMID 15123616DOI 10.1074/JBC.M403434200 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped Variants
General Structure Information 3msx ARHGAP20 crystal structure of rhoa.gdp.mgf3 in complex with gap domain of arhgap20 1.65Å AUTH D.UTEPBERGENOV,D.R.COOPER,U.DEREWENDA,A.V.SOMLYO,AUTH 2 Z.S.DEREWENDATITL MECHANISM OF MOLECULAR SPECIFICITY OF RHOGAP DOMAINS TOWARDSTITL 2 SMALL GTPASES OF RHOA FAMILY.REF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped Variants
General Structure Information 2dk3 HECTD1 solution structure of mib-herc2 domain in hect domain containing protein 1 -1.0Å AUTH F.HE,Y.MUTO,M.INOUE,T.KIGAWA,M.SHIROUZU,T.TERADA,AUTH 2 S.YOKOYAMATITL SOLUTION STRUCTURE OF MIB-HERC2 DOMAIN IN HECTTITL 2 DOMAIN CONTAINING PROTEIN 1REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2i2r KCNIP1 crystal structure of the kchip1/kv4.3 t1 complex 3.35Å AUTH M.PIOLETTI,F.FINDEISEN,G.L.HURA,D.L.MINOR JR.TITL THREE-DIMENSIONAL STRUCTURE OF THE KCHIP1-KV4.3 T1 COMPLEXTITL 2 REVEALS A CROSS-SHAPED OCTAMERREF NAT.STRUCT.MOL.BIOL. V. 13 987 2006REFN ISSN 1545-9993PMID 17057713DOI 10.1038/NSMB1164 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped Variants
General Structure Information 2kn6 PYCARD structure of full-length human asc (apoptosis-associated speck-like protein containing a card) -1.0Å AUTH E.DE ALBATITL STRUCTURE AND INTERDOMAIN DYNAMICS OF APOPTOSIS-ASSOCIATEDTITL 2 SPECK-LIKE PROTEIN CONTAINING A CARD (ASC)REF J.BIOL.CHEM. V. 284 32932 2009REFN ISSN 0021-9258PMID 19759015DOI 10.1074/JBC.M109.024273 Variant Set Distributions Mapped Variants
General Structure Information 3c5c RASL12 crystal structure of human ras-like, family 12 protein in complex with gdp 1.85Å AUTH L.SHEN,Y.TONG,W.TEMPEL,P.LOPPNAU,C.H.ARROWSMITH,AUTH 2 A.M.EDWARDS,C.BOUNTRA,J.WEIGELT,A.BOCHKAREV,H.PARKTITL CRYSTAL STRUCTURE OF HUMAN RAS-LIKE, FAMILY 12TITL 2 PROTEIN IN COMPLEX WITH GDP.REF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped Variants
General Structure Information 2cq1 PTBP2 solution structure of rna binding domain in ptb-like protein l -1.0Å AUTH K.TSUDA,Y.MUTO,M.INOUE,T.KIGAWA,T.TERADA,AUTH 2 M.SHIROUZU,S.YOKOYAMATITL SOLUTION STRUCTURE OF RNA BINDING DOMAIN INTITL 2 PTB-LIKE PROTEIN LREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 3vro CBLC crystal structure of the tyrosine kinase binding domain of cbl-c in complex with phospho-src peptide 1.8Å AUTH K.TAKESHITA,T.TEZUKA,Y.ISOZAKI,E.YAMASHITA,M.SUZUKI,M.KIM,AUTH 2 Y.YAMANASHI,T.YAMAMOTO,A.NAKAGAWATITL STRUCTURAL FLEXIBILITY REGULATES PHOSPHOPEPTIDE-BINDINGTITL 2 ACTIVITY OF THE TYROSINE KINASE BINDING DOMAIN OF CBL-C.REF J.BIOCHEM. V. 152 487 2012REFN ISSN 0021-924XPMID 22888118DOI 10.1093/JB/MVS085 Variant Set Distributions Mapped Variants