General Structure Information
| PDB ID | 1t3g |
| HGNC Gene Label(s) | IL1RAPL1 |
| Structure Name | crystal structure of the toll/interleukin-1 receptor (tir) domain of human il-1rapl |
| Resolution | 2.3Å |
| Reference | AUTH J.A.KHAN,E.K.BRINT,L.A.J.ONEILL,L.TONGTITL CRYSTAL STRUCTURE OF THE TOLL/INTERLEUKIN-1TITL 2 RECEPTOR DOMAIN OF HUMAN IL-1RAPLREF J.BIOL.CHEM. V. 279 31664 2004REFN ISSN 0021-9258PMID 15123616DOI 10.1074/JBC.M403434200 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 146 |
| Number Of SNVs | 6 |
| Number Of Permutations | 883 |
| Optimal Distance Threshold | 9.0 |
| K Statistic | 0.0 |
| p-value | 0.922 |
COSMIC
| Number Of Residues | 146 |
| Number Of SNVs | 4 |
| Number Of Permutations | 500 |
| Optimal Distance Threshold | 8.0 |
| K Statistic | 0.167 |
| p-value | 0.636 |
Ripley’s K Analysis Plots
ExACCOSMIC


Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 6 |
| Number Of COSMIC SNVs | 5 |
| Optimal Distance Threshold | 8.0 |
| K Statistic | 0.1 |
| p-value | 1.0 |