General Structure Information
| PDB ID | 3in5 |
| HGNC Gene Label(s) | POLK |
| Structure Name | structure of human dna polymerase kappa inserting datp opposite an 8-oxog dna lesion |
| Resolution | 3.2Å |
| Reference | AUTH R.VASQUEZ-DEL CARPIO,T.D.SILVERSTEIN,S.LONE,AUTH 2 M.K.SWAN,J.R.CHOUDHURY,R.E.JOHNSON,S.PRAKASH,AUTH 3 L.PRAKASH,A.K.AGGARWALTITL STRUCTURE OF HUMAN DNA POLYMERASE KAPPA INSERTINGTITL 2 DATP OPPOSITE AN 8-OXOG DNA LESIONREF PLOS ONE V. 4 E5766 2009REFN ESSN 1932-6203PMID 19492058DOI 10.1371/JOURNAL.PONE.0005766 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 437 |
| Number Of SNVs | 107 |
| Number Of Permutations | 23452 |
| Optimal Distance Threshold | 11.0 |
| K Statistic | 0.045 |
| p-value | 0.876 |
ClinVar
| Number Of Residues | 437 |
| Number Of SNVs | 4 |
| Number Of Permutations | 597 |
| Optimal Distance Threshold | 20.0 |
| K Statistic | 0.833 |
| p-value | 0.073 |
Ripley’s K Analysis Plots
ExACClinVar
Variant Set Comparisons
ClinVar vs. ExAC
| Number Of ExAC SNVs | 107 |
| Number Of ClinVar SNVs | 4 |
| Optimal Distance Threshold | 20.0 |
| K Statistic | 0.633 |
| p-value | 0.096 |
Pathogenic Proximity Analysis
ClinVar PathProx Analysis
