Assessment of Structural Intolerance and Durability
General Structure Information 2coy DCTN1 solution structure of the cap-gly domain in human dynactin 1 -1.0Å AUTH K.SAITO,S.KOSHIBA,M.INOUE,T.KIGAWA,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE CAP-GLY DOMAIN IN HUMANTITL 2 DYNACTIN 1REF TO BE PUBLISHEDREFN Variant Set Distributions Pathogenic Proximity Analysis Mapped Variants
General Structure Information 2coy DCTN1 solution structure of the cap-gly domain in human dynactin 1 -1.0Å AUTH K.SAITO,S.KOSHIBA,M.INOUE,T.KIGAWA,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE CAP-GLY DOMAIN IN HUMANTITL 2 DYNACTIN 1REF TO BE PUBLISHEDREFN Variant Set Distributions Pathogenic Proximity Analysis Mapped Variants
General Structure Information 3k05 MDC1 the crystal structure of mdc1 brct t2067d in complex with a minimal recognition tetrapeptide with an amidated c-terminus 1.33Å AUTH S.J.CAMPBELL,R.A.EDWARDS,J.N.GLOVERTITL COMPARISON OF THE STRUCTURES AND PEPTIDE BINDINGTITL 2 SPECIFICITIES OF THE BRCT DOMAINS OF MDC1 AND BRCA1REF STRUCTURE V. 18 167 2010REFN ISSN 0969-2126PMID 20159462DOI 10.1016/J.STR.2009.12.008 Variant Set Distributions […]
General Structure Information 2kr1 UBE3A solution nmr structure of zinc binding n-terminal domain of ubiquitin- protein ligase e3a from homo sapiens. northeast structural genomics consortium (nesg) target hr3662 -1.0Å AUTH A.LEMAK,A.YEE,I.BEZSONOVA,S.DHE-PAGANON,C.H.ARROWSMITHTITL ZN-BINDING AZUL DOMAIN OF HUMAN UBIQUITIN PROTEIN LIGASETITL 2 UBE3A.REF J.BIOMOL.NMR V. 51 185 2011REFN ISSN 0925-2738PMID 21947926DOI 10.1007/S10858-011-9552-Y Variant Set Distributions Ripley’s K […]
General Structure Information 4jol RUNX1T1 complex structure of aml1-eto nhr2 domain with heb fragment 2.91Å AUTH X.J.SUN,Z.WANG,L.WANG,Y.JIANG,N.KOST,T.D.SOONG,W.Y.CHEN,AUTH 2 Z.TANG,T.NAKADAI,O.ELEMENTO,W.FISCHLE,A.MELNICK,D.J.PATEL,AUTH 3 S.D.NIMER,R.G.ROEDERTITL A STABLE TRANSCRIPTION FACTOR COMPLEX NUCLEATED BYTITL 2 OLIGOMERIC AML1-ETO CONTROLS LEUKAEMOGENESIS.REF NATURE V. 500 93 2013REFN ISSN 0028-0836PMID 23812588DOI 10.1038/NATURE12287 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis […]
General Structure Information 1bwn BTK ph domain and btk motif from brutons tyrosine kinase mutant e41k in complex with ins(1,3,4,5)p4 2.1Å AUTH E.BARALDI,K.D.CARUGO,M.HYVONEN,P.L.SURDO,A.M.RILEY,AUTH 2 B.V.POTTER,R.OBRIEN,J.E.LADBURY,M.SARASTETITL STRUCTURE OF THE PH DOMAIN FROM BRUTONS TYROSINE KINASE INTITL 2 COMPLEX WITH INOSITOL 1,3,4,5-TETRAKISPHOSPHATE.REF STRUCTURE FOLD.DES. V. 7 449 1999REFN ISSN 0969-2126PMID 10196129DOI 10.1016/S0969-2126(99)80057-4 Variant Set Distributions Ripley’s K […]
General Structure Information 1bwn BTK ph domain and btk motif from brutons tyrosine kinase mutant e41k in complex with ins(1,3,4,5)p4 2.1Å AUTH E.BARALDI,K.D.CARUGO,M.HYVONEN,P.L.SURDO,A.M.RILEY,AUTH 2 B.V.POTTER,R.OBRIEN,J.E.LADBURY,M.SARASTETITL STRUCTURE OF THE PH DOMAIN FROM BRUTONS TYROSINE KINASE INTITL 2 COMPLEX WITH INOSITOL 1,3,4,5-TETRAKISPHOSPHATE.REF STRUCTURE FOLD.DES. V. 7 449 1999REFN ISSN 0969-2126PMID 10196129DOI 10.1016/S0969-2126(99)80057-4 Variant Set Distributions Ripley’s K […]
General Structure Information 1bwn BTK ph domain and btk motif from brutons tyrosine kinase mutant e41k in complex with ins(1,3,4,5)p4 2.1Å AUTH E.BARALDI,K.D.CARUGO,M.HYVONEN,P.L.SURDO,A.M.RILEY,AUTH 2 B.V.POTTER,R.OBRIEN,J.E.LADBURY,M.SARASTETITL STRUCTURE OF THE PH DOMAIN FROM BRUTONS TYROSINE KINASE INTITL 2 COMPLEX WITH INOSITOL 1,3,4,5-TETRAKISPHOSPHATE.REF STRUCTURE FOLD.DES. V. 7 449 1999REFN ISSN 0969-2126PMID 10196129DOI 10.1016/S0969-2126(99)80057-4 Variant Set Distributions Ripley’s K […]
General Structure Information 2r3v MVK the biochemical and structural basis for feedback inhibition of mevalonate kinase and isoprenoid metabolism 2.5Å AUTH Z.FU,N.E.VOYNOVA,T.J.HERDENDORF,H.M.MIZIORKO,AUTH 2 J.J.KIMTITL BIOCHEMICAL AND STRUCTURAL BASIS FOR FEEDBACKTITL 2 INHIBITION OF MEVALONATE KINASE AND ISOPRENOIDTITL 3 METABOLISM.REF BIOCHEMISTRY V. 47 3715 2008REFN ISSN 0006-2960PMID 18302342DOI 10.1021/BI7024386 Variant Set Distributions Ripley’s K Analysis Plots […]
General Structure Information 2r3v MVK the biochemical and structural basis for feedback inhibition of mevalonate kinase and isoprenoid metabolism 2.5Å AUTH Z.FU,N.E.VOYNOVA,T.J.HERDENDORF,H.M.MIZIORKO,AUTH 2 J.J.KIMTITL BIOCHEMICAL AND STRUCTURAL BASIS FOR FEEDBACKTITL 2 INHIBITION OF MEVALONATE KINASE AND ISOPRENOIDTITL 3 METABOLISM.REF BIOCHEMISTRY V. 47 3715 2008REFN ISSN 0006-2960PMID 18302342DOI 10.1021/BI7024386 Variant Set Distributions Ripley’s K Analysis Plots […]