General Structure Information
| PDB ID | 2kr1 |
| HGNC Gene Label(s) | UBE3A |
| Structure Name | solution nmr structure of zinc binding n-terminal domain of ubiquitin- protein ligase e3a from homo sapiens. northeast structural genomics consortium (nesg) target hr3662 |
| Resolution | -1.0Å |
| Reference | AUTH A.LEMAK,A.YEE,I.BEZSONOVA,S.DHE-PAGANON,C.H.ARROWSMITHTITL ZN-BINDING AZUL DOMAIN OF HUMAN UBIQUITIN PROTEIN LIGASETITL 2 UBE3A.REF J.BIOMOL.NMR V. 51 185 2011REFN ISSN 0925-2738PMID 21947926DOI 10.1007/S10858-011-9552-Y |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 64 |
| Number Of SNVs | 5 |
| Number Of Permutations | 277 |
| Optimal Distance Threshold | 12.0 |
| K Statistic | 0.1 |
| p-value | 0.547 |
COSMIC
| Number Of Residues | 64 |
| Number Of SNVs | 3 |
| Number Of Permutations | 107 |
| Optimal Distance Threshold | 5.0 |
| K Statistic | 0.333 |
| p-value | 0.321 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 5 |
| Number Of COSMIC SNVs | 3 |
| Optimal Distance Threshold | 5.0 |
| K Statistic | 0.333 |
| p-value | 0.325 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
