Assessment of Structural Intolerance and Durability
General Structure Information 3waa H2AFV the nucleosome containing human h2a.z.2 3.2Å AUTH N.HORIKOSHI,K.SATO,K.SHIMADA,Y.ARIMURA,A.OSAKABE,AUTH 2 H.TACHIWANA,Y.HAYASHI-TAKANAKA,W.IWASAKI,W.KAGAWA,M.HARATA,AUTH 3 H.KIMURA,H.KURUMIZAKATITL STRUCTURAL POLYMORPHISM IN THE L1 LOOP REGIONS OF HUMANTITL 2 H2A.Z.1 AND H2A.Z.2REF ACTA CRYSTALLOGR.,SECT.D V. 69 2431 2013REFN ISSN 0907-4449PMID 24311584DOI 10.1107/S090744491302252X Variant Set Distributions Mapped Variants
General Structure Information 3v33 ZC3H12A crystal structure of mcpip1 conserved domain with zinc-finger motif 2.0Å AUTH J.XU,W.PENG,Y.SUN,X.WANG,Y.XU,X.LI,G.GAO,Z.RAOTITL STRUCTURAL STUDY OF MCPIP1 N-TERMINAL CONSERVED DOMAINTITL 2 REVEALS A PIN-LIKE RNASEREF NUCLEIC ACIDS RES. V. 40 6957 2012REFN ISSN 0305-1048PMID 22561375DOI 10.1093/NAR/GKS359 Variant Set Distributions Mapped Variants
General Structure Information 2di7 KDELC1 solution structure of the filamin domain from human bk158_1 protein -1.0Å AUTH T.TOMIZAWA,S.KOSHIBA,M.INOUE,T.KIGAWA,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE FILAMIN DOMAIN FROMTITL 2 HUMAN BK158_1 PROTEINREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2yz8 OBSCN crystal structure of the 32th ig-like domain of human obscurin (kiaa1556) 2.0Å AUTH S.SAIJO,N.OHSAWA,A.NISHINO,S.KISHISHITA,L.CHEN,Z.Q.FU,AUTH 2 J.CHRZAS,B.C.WANG,M.SHIROUZU,S.YOKOYAMATITL CRYSTAL STRUCTURE OF THE 32TH IG-LIKE DOMAIN OF HUMANTITL 2 OBSCURIN (KIAA1556)REF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 2ld4 CIAPIN1 solution structure of the n-terminal domain of human anamorsin -1.0Å AUTH L.BANCI,I.BERTINI,S.CIOFI-BAFFONI,F.BOSCARO,A.CHATZI,AUTH 2 M.MIKOLAJCZYK,K.TOKATLIDIS,J.WINKELMANNTITL ANAMORSIN IS A [2FE-2S] CLUSTER-CONTAINING SUBSTRATE OF THETITL 2 MIA40-DEPENDENT MITOCHONDRIAL PROTEIN TRAPPING MACHINERY.REF CHEM.BIOL. V. 18 794 2011REFN ISSN 1074-5521PMID 21700214DOI 10.1016/J.CHEMBIOL.2011.03.015 Variant Set Distributions Mapped Variants
General Structure Information 4doh IL20RB il20/il201/il20r2 ternary complex 2.8Å AUTH N.J.LOGSDON,A.DESHPANDE,B.D.HARRIS,K.R.RAJASHANKAR,AUTH 2 M.R.WALTERTITL STRUCTURAL BASIS FOR RECEPTOR SHARING AND ACTIVATION BYTITL 2 INTERLEUKIN-20 RECEPTOR-2 (IL-20R2) BINDING CYTOKINES.REF PROC.NATL.ACAD.SCI.USA V. 109 12704 2012REFN ISSN 0027-8424PMID 22802649DOI 10.1073/PNAS.1117551109 Variant Set Distributions Mapped Variants
General Structure Information 3puf RNASEH2B crystal structure of human rnase h2 complex 3.1Å AUTH M.FIGIEL,H.CHON,S.M.CERRITELLI,M.CYBULSKA,R.J.CROUCH,AUTH 2 M.NOWOTNYTITL THE STRUCTURAL AND BIOCHEMICAL CHARACTERIZATION OF HUMANTITL 2 RNASE H2 COMPLEX REVEALS THE MOLECULAR BASIS FOR SUBSTRATETITL 3 RECOGNITION AND AICARDI-GOUTIERES SYNDROME DEFECTS.REF J.BIOL.CHEM. V. 286 10540 2011REFN ISSN 0021-9258PMID 21177858DOI 10.1074/JBC.M110.181974 Variant Set Distributions Pathogenic Proximity Analysis […]
General Structure Information 3bdl SND1 crystal structure of a truncated human tudor-sn 1.9Å AUTH C.L.LI,W.Z.YANG,Y.P.CHEN,H.S.YUANTITL STRUCTURAL AND FUNCTIONAL INSIGHTS INTO HUMANTITL 2 TUDOR-SN, A KEY COMPONENT LINKING RNA INTERFERENCETITL 3 AND EDITING.REF NUCLEIC ACIDS RES. V. 36 3579 2008REFN ISSN 0305-1048PMID 18453631DOI 10.1093/NAR/GKN236 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity […]
General Structure Information 3qj4 RNLS crystal structure of human renalase (isoform 1) 2.5Å AUTH M.MILANI,F.CIRIELLO,S.BARONI,V.PANDINI,G.CANEVARI,AUTH 2 M.BOLOGNESI,A.ALIVERTITITL FAD-BINDING SITE AND NADP REACTIVITY IN HUMAN RENALASE: ATITL 2 NEW ENZYME INVOLVED IN BLOOD PRESSURE REGULATIONREF J.MOL.BIOL. V. 411 463 2011REFN ISSN 0022-2836PMID 21699903DOI 10.1016/J.JMB.2011.06.010 Variant Set Distributions Mapped Variants
General Structure Information 3of6 PTCRA human pre-t cell receptor crystal structure 2.8Å AUTH S.S.PANG,R.BERRY,Z.CHEN,L.KJER-NIELSEN,M.A.PERUGINI,AUTH 2 G.F.KING,C.WANG,S.H.CHEW,N.L.LA GRUTA,N.K.WILLIAMS,T.BEDDOE,AUTH 3 T.TIGANIS,N.P.COWIESON,D.I.GODFREY,A.W.PURCELL,M.C.J.WILCE,AUTH 4 J.MCCLUSKEY,J.ROSSJOHNTITL THE STRUCTURAL BASIS FOR AUTONOMOUS DIMERIZATION OF THETITL 2 PRE-T-CELL ANTIGEN RECEPTORREF NATURE V. 467 844 2010REFN ISSN 0028-0836PMID 20944746DOI 10.1038/NATURE09448 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped Variants