General Structure Information
| PDB ID | 3puf |
| HGNC Gene Label(s) | RNASEH2B |
| Structure Name | crystal structure of human rnase h2 complex |
| Resolution | 3.1Å |
| Reference | AUTH M.FIGIEL,H.CHON,S.M.CERRITELLI,M.CYBULSKA,R.J.CROUCH,AUTH 2 M.NOWOTNYTITL THE STRUCTURAL AND BIOCHEMICAL CHARACTERIZATION OF HUMANTITL 2 RNASE H2 COMPLEX REVEALS THE MOLECULAR BASIS FOR SUBSTRATETITL 3 RECOGNITION AND AICARDI-GOUTIERES SYNDROME DEFECTS.REF J.BIOL.CHEM. V. 286 10540 2011REFN ISSN 0021-9258PMID 21177858DOI 10.1074/JBC.M110.181974 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 200 |
| Number Of SNVs | 51 |
| Number Of Permutations | 9170 |
| Optimal Distance Threshold | 13.0 |
| K Statistic | 0.123 |
| p-value | 0.403 |
ClinVar
| Number Of Residues | 200 |
| Number Of SNVs | 3 |
| Number Of Permutations | 174 |
| Optimal Distance Threshold | 12.0 |
| K Statistic | 0.333 |
| p-value | 0.709 |
Ripley’s K Analysis Plots
ExACClinVar
Variant Set Comparisons
ClinVar vs. ExAC
| Number Of ExAC SNVs | 51 |
| Number Of ClinVar SNVs | 3 |
| Optimal Distance Threshold | 12.0 |
| K Statistic | 0.227 |
| p-value | 0.598 |
Pathogenic Proximity Analysis
ClinVar PathProx Analysis
