Assessment of Structural Intolerance and Durability
General Structure Information 2ebk RWDD3 solution structure of the rwd domain of human rwd domain containing protein 3 -1.0Å AUTH M.YONEYAMA,S.KOSHIBA,S.WATABE,T.HARADA,T.KIGAWA,AUTH 2 S.YOKOYAMATITL SOLUTION STRUCTURE OF THE RWD DOMAIN OF HUMAN RWDTITL 2 DOMAIN CONTAINING PROTEIN 3REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2z0d ATG4B the crystal structure of human atg4b- lc3(1-120) complex 1.9Å AUTH K.SATOO,N.N.NODA,H.KUMETA,Y.FUJIOKA,N.MIZUSHIMA,AUTH 2 Y.OHSUMI,F.INAGAKITITL THE STRUCTURE OF ATG4B-LC3 COMPLEX REVEALS THETITL 2 MECHANISM OF LC3 PROCESSING AND DELIPIDATION DURINGTITL 3 AUTOPHAGY.REF EMBO J. V. 28 1341 2009REFN ISSN 0261-4189PMID 19322194DOI 10.1038/EMBOJ.2009.80 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons […]
General Structure Information 2ouc DUSP10 crystal structure of the map kinase binding domain of mkp5 2.2Å AUTH X.TAO,L.TONGTITL CRYSTAL STRUCTURE OF THE MAP KINASE BINDING DOMAINTITL 2 AND THE CATALYTIC DOMAIN OF HUMAN MKP5.REF PROTEIN SCI. V. 16 880 2007REFN ISSN 0961-8368PMID 17400920DOI 10.1110/PS.062712807 Variant Set Distributions Mapped Variants
General Structure Information 2kbc INSL5 solution structure of human insulin-like peptide 5 (insl5) -1.0Å AUTH M.A.HOSSAIN,N.L.DALY,D.J.CRAIK,J.D.WADE,AUTH 2 K.J.ROSENGRENTITL STRUCTURE OF HUMAN INSULIN-LIKE PEPTIDE 5 ANDTITL 2 CHARACTERIZATION OF CONSERVED HYDROGEN BONDS ANDTITL 3 ELECTROSTATIC INTERACTIONS WITHIN THE RELAXINTITL 4 FRAMEWORKREF BIOCHEM.J. V. 419 619 2009REFN ISSN 0264-6021PMID 19178384DOI 10.1042/BJ20082353 Variant Set Distributions Mapped Variants
General Structure Information 4hhv COL4A3BP crystal structure of ceramide transfer protein pleckstrin homology domain 1.75Å AUTH J.PRASHEK,T.TRUONG,X.YAOTITL CRYSTAL STRUCTURE OF THE PLECKSTRIN HOMOLOGY DOMAIN FROM THETITL 2 CERAMIDE TRANSFER PROTEIN: IMPLICATIONS FOR CONFORMATIONALTITL 3 CHANGE UPON LIGAND BINDING.REF PLOS ONE V. 8 79590 2013REFN ESSN 1932-6203PMID 24260258DOI 10.1371/JOURNAL.PONE.0079590 Variant Set Distributions Mapped Variants
General Structure Information 4l9c FBXO7 crystal structure of the fp domain of human f-box protein fbxo7 (native) 2.1Å AUTH J.SHANG,G.WANG,Y.YANG,X.HUANG,Z.DUTITL STRUCTURE OF THE FP DOMAIN OF FBXO7 REVEALS A NOVEL MODE OFTITL 2 PROTEIN-PROTEIN INTERACTION.REF ACTA CRYSTALLOGR.,SECT.D V. 70 155 2014REFN ISSN 0907-4449PMID 24419388DOI 10.1107/S1399004713025820 Variant Set Distributions Mapped Variants
General Structure Information 3a7h STK24 human mst3 kinase in complex with atp 1.96Å AUTH T.P.KO,W.Y.JENG,C.I.LIU,M.D.LAI,C.L.WU,W.J.CHANG,H.L.SHR,AUTH 2 T.J.LU,A.H.J.WANGTITL STRUCTURES OF HUMAN MST3 KINASE IN COMPLEX WITH ADENINE, ADPTITL 2 AND MN2+.REF ACTA CRYSTALLOGR.,SECT.D V. 66 145 2010REFN ISSN 0907-4449PMID 20124694DOI 10.1107/S0907444909047507 Variant Set Distributions Mapped Variants
General Structure Information 2ch6 NAGK crystal structure of human n-acetylglucosamine kinase in complex with adp and glucose 2.72Å AUTH W.A.WEIHOFEN,M.BERGER,H.CHEN,W.SAENGER,S.HINDERLICHTITL STRUCTURES OF HUMAN N-ACETYLGLUCOSAMINE KINASE IN TWOTITL 2 COMPLEXES WITH N-ACETYLGLUCOSAMINE AND WITH ADP/GLUCOSE:TITL 3 INSIGHTS INTO SUBSTRATE SPECIFICITY AND REGULATION.REF J.MOL.BIOL. V. 364 388 2006REFN ISSN 0022-2836PMID 17010375DOI 10.1016/J.JMB.2006.08.085 Variant Set Distributions Ripley’s K […]
General Structure Information 3g5c ADAM22 structural and biochemical studies on the ectodomain of human adam22 2.36Å AUTH H.LIU,A.SHIM,X.CHEN,X.HETITL STRUCTURAL AND BIOCHEMICAL STUDIES ON THE ECTODOMAIN OFTITL 2 HUMAN ADAM22REF J.BIOL.CHEM. 2009REFN ESSN 1083-351X Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped Variants
General Structure Information 2rb4 DDX25 crystal structure of the helicase domain of human ddx25 rna helicase 2.8Å AUTH P.SCHUTZ,T.KARLBERG,S.VAN DEN BERG,R.COLLINS,L.LEHTIO,AUTH 2 M.HOGBOM,L.HOLMBERG-SCHIAVONE,W.TEMPEL,H.W.PARK,AUTH 3 M.HAMMARSTROM,M.MOCHE,A.G.THORSELL,H.SCHULERTITL COMPARATIVE STRUCTURAL ANALYSIS OF HUMAN DEAD-BOX RNATITL 2 HELICASES.REF PLOS ONE V. 5 12791 2010REFN ESSN 1932-6203PMID 20941364DOI 10.1371/JOURNAL.PONE.0012791 Variant Set Distributions Mapped Variants