Assessment of Structural Intolerance and Durability
General Structure Information 2m5v NLRP10 three-dimensional structure of human nlrp10/pynod pyrin domain -1.0Å AUTH M.Y.SU,C.I.KUO,C.F.CHANG,C.I.CHANGTITL THREE-DIMENSIONAL STRUCTURE OF HUMAN NLRP10/PYNOD PYRINTITL 2 DOMAIN REVEALS A HOMOTYPIC INTERACTION SITE DISTINCT FROMTITL 3 ITS MOUSE HOMOLOGUE.REF PLOS ONE V. 8 67843 2013REFN ESSN 1932-6203PMID 23861819DOI 10.1371/JOURNAL.PONE.0067843 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic […]
General Structure Information 4lla LILRB2 crystal structure of d3d4 domain of the lilrb2 molecule 2.5Å AUTH G.NAM,Y.SHI,M.RYU,Q.WANG,H.SONG,J.LIU,J.YAN,J.QI,G.F.GAOTITL CRYSTAL STRUCTURES OF THE TWO MEMBRANE-PROXIMAL IG-LIKETITL 2 DOMAINS (D3D4) OF LILRB1/B2: ALTERNATIVE MODELS FOR THEIRTITL 3 INVOLVEMENT IN PEPTIDE-HLA BINDINGREF PROTEIN CELL V. 4 761 2013REFN ISSN 1674-800XPMID 23955630DOI 10.1007/S13238-013-3908-X Variant Set Distributions Ripley’s K Analysis Plots […]
General Structure Information 4ll9 LILRB1 crystal structure of d3d4 domain of the lilrb1 molecule 2.69Å AUTH G.NAM,Y.SHI,M.RYU,Q.WANG,H.SONG,J.LIU,J.YAN,J.QI,G.F.GAOTITL CRYSTAL STRUCTURES OF THE TWO MEMBRANE-PROXIMAL IG-LIKETITL 2 DOMAINS (D3D4) OF LILRB1/B2: ALTERNATIVE MODELS FOR THEIRTITL 3 INVOLVEMENT IN PEPTIDE-HLA BINDINGREF PROTEIN CELL V. 4 761 2013REFN ISSN 1674-800XPMID 23955630DOI 10.1007/S13238-013-3908-X Variant Set Distributions Ripley’s K Analysis Plots […]
General Structure Information 3g1n HUWE1 catalytic domain of the human e3 ubiquitin-protein ligase huwe1 2.6Å AUTH J.R.WALKER,L.QIU,Y.LI,T.DAVIS,W.TEMPEL,J.WEIGELT,AUTH 2 C.BOUNTRA,C.H.ARROWSMITH,A.M.EDWARDS,A.BOTCHKAREV,AUTH 3 S.DHE-PAGANONTITL HECT DOMAIN OF HUMAN HUWE1/MULEREF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 2db2 DHX30 solution structure of the double-stranded rna binding domain in kiaa0890 protein -1.0Å AUTH C.ABE,Y.MUTO,M.INOUE,T.KIGAWA,T.TERADA,M.SHIROUZU,AUTH 2 S.YOKOYAMATITL SOLUTION STRUCTURE OF THE DOUBLE-STRANDED RNATITL 2 BINDING DOMAIN IN KIAA0890 PROTEINREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 3tw8 DENND1B gef domain of dennd 1b in complex with rab gtpase rab35 2.1Å AUTH X.WU,M.J.BRADLEY,Y.CAI,D.KUMMEL,E.M.DE LA CRUZ,F.A.BARR,AUTH 2 K.M.REINISCHTITL INSIGHTS REGARDING GUANINE NUCLEOTIDE EXCHANGE FROM THETITL 2 STRUCTURE OF A DENN-DOMAIN PROTEIN COMPLEXED WITH ITS RABTITL 3 GTPASE SUBSTRATE.REF PROC.NATL.ACAD.SCI.USA V. 108 18672 2011REFN ISSN 0027-8424PMID 22065758DOI 10.1073/PNAS.1110415108 Variant Set Distributions […]
General Structure Information 3s8p SUV420H1 crystal structure of the set domain of human histone-lysine n- methyltransferase suv420h1 in complex with s-adenosyl-l-methionine 1.85Å AUTH H.WU,A.SIARHEYEVA,H.ZENG,R.LAM,A.DONG,X.H.WU,Y.LI,AUTH 2 M.SCHAPIRA,M.VEDADI,J.MINTITL CRYSTAL STRUCTURES OF THE HUMAN HISTONE H4K20TITL 2 METHYLTRANSFERASES SUV420H1 AND SUV420H2.REF FEBS LETT. V. 587 3859 2013REFN ISSN 0014-5793PMID 24396869 Variant Set Distributions Ripley’s K Analysis Plots Variant […]
General Structure Information 2da2 ZFHX3 solution structure of the second homeobox domain of at- binding transcription factor 1 (atbf1) -1.0Å AUTH S.OHNISHI,T.KIGAWA,N.TOCHIO,S.KOSHIBA,M.INOUE,AUTH 2 S.YOKOYAMATITL SOLUTION STRUCTURE OF THE SECOND HOMEOBOX DOMAINTITL 2 OF AT-BINDING TRANSCRIPTION FACTOR 1 (ATBF1)REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2dha ESRP1 solution structure of the second rna recognition motif in hypothetical protein flj201171 -1.0Å AUTH T.IMAI,K.TSUDA,Y.MUTO,M.INOUE,T.KIGAWA,T.TERADA,AUTH 2 M.SHIROUZU,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE SECOND RNA RECOGNITIONTITL 2 MOTIF IN HYPOTHETICAL PROTEIN FLJ201171REF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 2yuy ARHGAP21 solution structure of pdz domain of rho gtpase activating protein 21 -1.0Å AUTH T.N.NIRAULA,M.YONEYAMA,S.KOSHIBA,M.INOUE,T.KIGAWA,AUTH 2 S.YOKOYAMATITL SOLUTION STRUCTURE OF PDZ DOMAIN OF RHO GTPASETITL 2 ACTIVATING PROTEIN 21REF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants