General Structure Information
| PDB ID | 2yuy |
| HGNC Gene Label(s) | ARHGAP21 |
| Structure Name | solution structure of pdz domain of rho gtpase activating protein 21 |
| Resolution | -1.0Å |
| Reference | AUTH T.N.NIRAULA,M.YONEYAMA,S.KOSHIBA,M.INOUE,T.KIGAWA,AUTH 2 S.YOKOYAMATITL SOLUTION STRUCTURE OF PDZ DOMAIN OF RHO GTPASETITL 2 ACTIVATING PROTEIN 21REF TO BE PUBLISHEDREFN |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 113 |
| Number Of SNVs | 22 |
| Number Of Permutations | 3288 |
| Optimal Distance Threshold | 12.0 |
| K Statistic | 0.113 |
| p-value | 0.088 |
COSMIC
| Number Of Residues | 113 |
| Number Of SNVs | 3 |
| Number Of Permutations | 188 |
| Optimal Distance Threshold | 26.0 |
| K Statistic | 0.333 |
| p-value | 0.607 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 22 |
| Number Of COSMIC SNVs | 3 |
| Optimal Distance Threshold | 22.0 |
| K Statistic | -0.459 |
| p-value | 0.265 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
