Assessment of Structural Intolerance and Durability
General Structure Information 2d88 MICAL3 solution structure of the ch domain from human mical-3 protein -1.0Å AUTH T.TOMIZAWA,T.KIGAWA,S.KOSHIBA,M.INOUE,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE CH DOMAIN FROM HUMANTITL 2 MICAL-3 PROTEINREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2d89 EHBP1 solution structure of the ch domain from human eh domain binding protein 1 -1.0Å AUTH T.TOMIZAWA,T.KIGAWA,S.KOSHIBA,M.INOUE,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE CH DOMAIN FROM HUMAN EHTITL 2 DOMAIN BINDING PROTEIN 1REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2k2m EPS8L1 structural basis of pxxdy motif recognition in sh3 binding -1.0Å AUTH O.AITIO,M.HELLMAN,T.KESTI,I.KLEINO,O.SAMUILOVA,AUTH 2 K.PAAKKONEN,H.TOSSAVAINEN,K.SAKSELA,P.PERMITITL STRUCTURAL BASIS OF PXXDY MOTIF RECOGNITION IN SH3TITL 2 BINDING.REF J.MOL.BIOL. V. 382 167 2008REFN ISSN 0022-2836PMID 18644376DOI 10.1016/J.JMB.2008.07.008 Variant Set Distributions Mapped Variants
General Structure Information 2jp2 SPRED2 solution structure and resonance assignment of the n- terminal evh1 domain from the human spred2 protein (sprouty-related protein with evh1 domain isoform 2) -1.0Å AUTH J.ZIMMERMANN,T.JARCHAU,U.WALTER,H.OSCHKINAT,AUTH 2 L.J.BALLTITL 1H, 13C AND 15N RESONANCE ASSIGNMENT OF THE HUMANTITL 2 SPRED2 EVH1 DOMAINREF J.BIOMOL.NMR V. 29 435 2004REFN ISSN 0925-2738PMID 15213456DOI 10.1023/B:JNMR.0000032526.17586.8C […]
General Structure Information 4m7h FIBCD1 crystal structure of tetrameric fibrinogen-like recognition domain of fibcd1 2.0Å AUTH A.K.SHRIVE,J.B.MOELLER,I.BURNS,J.M.PATERSON,A.J.SHAW,AUTH 2 A.SCHLOSSER,G.L.SORENSEN,T.J.GREENHOUGH,U.HOLMSKOVTITL CRYSTAL STRUCTURE OF THE TETRAMERIC FIBRINOGEN-LIKETITL 2 RECOGNITION DOMAIN OF FIBRINOGEN C DOMAIN CONTAINING 1TITL 3 (FIBCD1) PROTEIN.REF J.BIOL.CHEM. V. 289 2880 2014REFN ISSN 0021-9258PMID 24293368DOI 10.1074/JBC.M113.520577 Variant Set Distributions Ripley’s K Analysis Plots Variant Set […]
General Structure Information 1ueq MAGI2 solution structure of the first pdz domain of human atrophin-1 interacting protein 1 (kiaa0705 protein) -1.0Å AUTH C.ZHAO,T.KIGAWA,N.TOCHIO,S.KOSHIBA,M.INOUE,AUTH 2 S.YOKOYAMATITL SOLUTION STRUCTURE OF THE FIRST PDZ DOMAIN OFTITL 2 HUMAN ATROPHIN-1 INTERACTING PROTEIN 1 (KIAA0705TITL 3 PROTEIN)REF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons […]
General Structure Information 2vsv RHPN2 crystal structure of the pdz domain of human rhophilin-2 1.82Å AUTH A.C.W.PIKE,G.KOCHAN,Z.SUN,N.SHAFQAT,E.S.PILKA,AUTH 2 A.ROOS,J.ELKINS,N.BURGESS-BROWN,J.W.MURRAY,AUTH 3 F.VON DELFT,M.WIKSTROM,A.EDWARDS,C.H.ARROWSMITH,AUTH 4 C.BOUNTRA,U.OPPERMANNTITL CRYSTAL STRUCTURE OF THE PDZ DOMAIN OF HUMANTITL 2 RHOPHILIN-2REF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 3gcx PCSK9 pcsk9:egfa (ph 7.4) 2.7Å AUTH M.C.MCNUTT,H.J.KWON,C.CHEN,J.R.CHEN,J.D.HORTON,T.A.LAGACETITL ANTAGONISM OF SECRETED PCSK9 INCREASES LOW DENSITYTITL 2 LIPOPROTEIN RECEPTOR EXPRESSION IN HEPG2 CELLS.REF J.BIOL.CHEM. V. 284 10561 2009REFN ISSN 0021-9258PMID 19224862DOI 10.1074/JBC.M808802200 Variant Set Distributions Mapped Variants
General Structure Information 1z9m CADM3 crystal structure of nectin-like molecule-1 protein domain 1 2.4Å AUTH X.DONG,F.XU,Y.GONG,J.GAO,P.LIN,T.CHEN,Y.PENG,AUTH 2 B.QIANG,J.YUAN,X.PENG,Z.RAOTITL CRYSTAL STRUCTURE OF THE V DOMAIN OF HUMANTITL 2 NECTIN-LIKE MOLECULE-1/SYNCAM3/TSLL1/IGSF4B, ATITL 3 NEURAL TISSUE-SPECIFIC IMMUNOGLOBULIN-LIKETITL 4 CELL-CELL ADHESION MOLECULEREF J.BIOL.CHEM. V. 281 10610 2006REFN ISSN 0021-9258PMID 16467305DOI 10.1074/JBC.M513459200 Variant Set Distributions Ripley’s K Analysis Plots Variant […]
General Structure Information 4esr AHI1 molecular and structural characterization of the sh3 domain of ahi-1 in regulation of cellular resistance of bcr-abl+ chronic myeloid leukemia cells to tyrosine kinase inhibitors 1.53Å AUTH X.LIU,M.CHEN,P.LOBO,J.AN,S.W.GRACE CHENG,A.MORADIAN,AUTH 2 G.B.MORIN,F.VAN PETEGEM,X.JIANGTITL MOLECULAR AND STRUCTURAL CHARACTERIZATION OF THE SH3 DOMAINTITL 2 OF AHI-1 IN REGULATION OF CELLULAR RESISTANCE OF BCR-ABL(+)TITL […]