General Structure Information
| PDB ID | 2vsv |
| HGNC Gene Label(s) | RHPN2 |
| Structure Name | crystal structure of the pdz domain of human rhophilin-2 |
| Resolution | 1.82Å |
| Reference | AUTH A.C.W.PIKE,G.KOCHAN,Z.SUN,N.SHAFQAT,E.S.PILKA,AUTH 2 A.ROOS,J.ELKINS,N.BURGESS-BROWN,J.W.MURRAY,AUTH 3 F.VON DELFT,M.WIKSTROM,A.EDWARDS,C.H.ARROWSMITH,AUTH 4 C.BOUNTRA,U.OPPERMANNTITL CRYSTAL STRUCTURE OF THE PDZ DOMAIN OF HUMANTITL 2 RHOPHILIN-2REF TO BE PUBLISHEDREFN |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 81 |
| Number Of SNVs | 27 |
| Number Of Permutations | 1142 |
| Optimal Distance Threshold | 9.0 |
| K Statistic | 0.131 |
| p-value | 0.791 |
COSMIC
| Number Of Residues | 81 |
| Number Of SNVs | 6 |
| Number Of Permutations | 805 |
| Optimal Distance Threshold | 10.0 |
| K Statistic | 0.133 |
| p-value | 0.883 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 27 |
| Number Of COSMIC SNVs | 4 |
| Optimal Distance Threshold | 11.0 |
| K Statistic | 0.238 |
| p-value | 0.494 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
