General Structure Information
| PDB ID | 4esr |
| HGNC Gene Label(s) | AHI1 |
| Structure Name | molecular and structural characterization of the sh3 domain of ahi-1 in regulation of cellular resistance of bcr-abl+ chronic myeloid leukemia cells to tyrosine kinase inhibitors |
| Resolution | 1.53Å |
| Reference | AUTH X.LIU,M.CHEN,P.LOBO,J.AN,S.W.GRACE CHENG,A.MORADIAN,AUTH 2 G.B.MORIN,F.VAN PETEGEM,X.JIANGTITL MOLECULAR AND STRUCTURAL CHARACTERIZATION OF THE SH3 DOMAINTITL 2 OF AHI-1 IN REGULATION OF CELLULAR RESISTANCE OF BCR-ABL(+)TITL 3 CHRONIC MYELOID LEUKEMIA CELLS TO TYROSINE KINASETITL 4 INHIBITORS.REF PROTEOMICS V. 12 2094 2012REFNPMID 22623184DOI 10.1002/PMIC.201100553 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 65 |
| Number Of SNVs | 20 |
| Number Of Permutations | 1367 |
| Optimal Distance Threshold | 11.0 |
| K Statistic | 0.326 |
| p-value | 0.728 |