Assessment of Structural Intolerance and Durability
General Structure Information 4hwn FCRLA crystal structure of the second ig-c2 domain of human fc-receptor like a (fcrla), isoform 9 [nysgrc-005836] 2.01Å AUTH P.R.KUMAR,S.G.NATHENSON,S.C.ALMOTITL CRYSTAL STRUCTURE OF THE SECOND IG-C2 DOMAIN OF THE HUMANTITL 2 FC-RECEPTOR LIKE A, ISOFORM 9 [NYSGRC-005836]REF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped […]
General Structure Information 1vf6 INADL 2.1 angstrom crystal structure of the pals-1-l27n and patj l27 heterodimer complex 2.1Å AUTH Y.LI,D.KARNAK,B.DEMELER,B.MARGOLIS,A.LAVIETITL STRUCTURAL BASIS FOR L27 DOMAIN-MEDIATED ASSEMBLYTITL 2 OF SIGNALING AND CELL POLARITY COMPLEXES.REF EMBO J. V. 23 2723 2004REFN ISSN 0261-4189PMID 15241471DOI 10.1038/SJ.EMBOJ.7600294 Variant Set Distributions Mapped Variants
General Structure Information 3ixe LIMS2 structural basis of competition between pinch1 and pinch2 for binding to the ankyrin repeat domain of integrin-linked kinase 1.9Å AUTH B.P.CHISWELL,A.L.STIEGLER,Z.RAZINIA,E.NALIBOTSKI,AUTH 2 T.J.BOGGON,D.A.CALDERWOODTITL STRUCTURAL BASIS OF COMPETITION BETWEEN PINCH1 ANDTITL 2 PINCH2 FOR BINDING TO THE ANKYRIN REPEAT DOMAIN OFTITL 3 INTEGRIN-LINKED KINASE.REF J.STRUCT.BIOL. V. 170 157 2010REFN ISSN 1047-8477PMID […]
General Structure Information 1wxt EPS8L3 solution structure of the sh3 domain of human hypothetical protein flj21522 -1.0Å AUTH M.YONEYAMA,K.SAITO,N.TOCHIO,S.KOSHIBA,M.INOUE,AUTH 2 T.KIGAWA,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE SH3 DOMAIN OF HUMANTITL 2 HYPOTHETICAL PROTEIN FLJ21522REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 3l11 RNF168 crystal structure of the ring domain of rnf168 2.12Å AUTH S.J.CAMPBELL,R.A.EDWARDS,C.C.LEUNG,D.NECULAI,C.D.HODGE,AUTH 2 S.DHE-PAGANON,J.N.GLOVERTITL MOLECULAR INSIGHTS INTO THE FUNCTION OF RING FINGERTITL 2 (RNF)-CONTAINING PROTEINS HRNF8 AND HRNF168 INTITL 3 UBC13/MMS2-DEPENDENT UBIQUITYLATION.REF J.BIOL.CHEM. V. 287 23900 2012REFN ISSN 0021-9258PMID 22589545DOI 10.1074/JBC.M112.359653 Variant Set Distributions Mapped Variants
General Structure Information 2yyo SPRYD3 crystal sturcture of human spry domain 2.0Å AUTH S.KISHISHITA,T.UCHIKUBO-KAMO,K.MURAYAMA,T.TERADA,AUTH 2 L.CHEN,Z.Q.FU,J.CHRZAS,M.SHIROUZU,B.C.WANG,AUTH 3 S.YOKOYAMATITL CRYSTAL STURCTURE OF HUMAN SPRY DOMAINREF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped Variants
General Structure Information 2kom PARD3 solution structure of humar par-3b pdz2 (residues 451-549) -1.0Å AUTH D.R.JENSEN,C.WOYTOVICH,M.LI,P.DUVNJAK,M.S.CASSIDY,AUTH 2 R.O.FREDERICK,L.F.BERGEMAN,F.C.PETERSON,B.F.VOLKMANTITL RAPID, ROBOTIC, SMALL-SCALE PROTEIN PRODUCTION FORTITL 2 NMR SCREENING AND STRUCTURE DETERMINATION.REF PROTEIN SCI. V. 19 570 2010REFN ISSN 0961-8368PMID 20073081DOI 10.1002/PRO.335 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 2dnx STX12 solution structure of rsgi ruh-063, an n-terminal domain of syntaxin 12 from human cdna -1.0Å AUTH T.ABE,H.HIROTA,Y.MUTO,S.YOKOYAMATITL SOLUTION STRUCTURE OF RSGI RUH-063, AN N-TERMINALTITL 2 DOMAIN OF SYNTAXIN 12 FROM HUMAN CDNAREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2eqo TRAF3IP1 solution structure of the stn_traf3ip1_nd domain of interleukin 13 receptor alpha 1-binding protein-1 [homo sapiens] -1.0Å AUTH W.DANG,Y.MUTO,M.INOUE,T.KIGAWA,M.SHIROUZU,T.TERADA,AUTH 2 S.YOKOYAMATITL SOLUTION STRUCTURE OF THE STN_TRAF3IP1_ND DOMAINTITL 2 OF INTERLEUKIN 13 RECEPTOR ALPHA 1-BINDINGTITL 3 PROTEIN-1 [HOMO SAPIENS]REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2da4 HDX solution structure of the homeobox domain of the hypothetical protein, dkfzp686k21156 -1.0Å AUTH S.OHNISHI,T.KIGAWA,K.SAITO,S.KOSHIBA,M.INOUE,AUTH 2 S.YOKOYAMATITL SOLUTION STRUCTURE OF THE HOMEOBOX DOMAIN OF THETITL 2 HYPOTHETICAL PROTEIN, DKFZP686K21156REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants