1WXT.A | EPS8L3

PDB ID	1wxt
HGNC Gene Label(s)	EPS8L3
Structure Name	solution structure of the sh3 domain of human hypothetical protein flj21522
Resolution	-1.0Å
Reference	AUTH M.YONEYAMA,K.SAITO,N.TOCHIO,S.KOSHIBA,M.INOUE,AUTH 2 T.KIGAWA,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE SH3 DOMAIN OF HUMANTITL 2 HYPOTHETICAL PROTEIN FLJ21522REF TO BE PUBLISHEDREFN

ExAC Variants

Position	Variant	AA Change	PDB Chain Position	Structure Coordinates
1:110294693	rs374700373	L>P	A:8	(3.88, 4.90, 1.56)
1:110294676		Y>H	A:14	(-10.07, -6.22, -1.90)
1:110294671		E>D	A:15	(-8.10, -11.35, 2.71)
1:110294672		E>G	A:15	(-8.10, -11.35, 2.71)
1:110294673		E>K	A:15	(-8.10, -11.35, 2.71)
1:110294651	rs148823610	R>Q	A:22	(8.25, -14.31, -3.17)
1:110294652	COSM527483 COSM1320152	R>W	A:22	(8.25, -14.31, -3.17)
1:110294642	rs77184613	T>N	A:25	(-1.03, -13.84, 4.86)
1:110294625		K>E	A:31	(-4.50, 0.66, 9.98)
1:110294385	rs145242219	R>Q	A:40	(4.56, -4.93, -12.76)
1:110294363		E>D	A:47	(2.37, -4.72, 13.78)
1:110294364		E>G	A:47	(2.37, -4.72, 13.78)
1:110294355	rs373046989 COSM893579	R>Q	A:50	(5.75, -11.98, 10.41)
1:110294356	rs75744349	R>W	A:50	(5.75, -11.98, 10.41)
1:110294350		G>S	A:52	(5.99, -9.36, 2.54)
1:110294336		S>R	A:56	(-0.42, -2.70, -5.28)
1:110294332	rs548689027	I>V	A:58	(-4.51, -5.95, -1.90)
1:110294324		E>D	A:60	(-6.56, 1.87, -1.39)
1:110294322		P>L	A:61	(-5.03, 5.81, -1.26)

[+] ExAC Missense Variants