General Structure Information
| PDB ID | 2yyo |
| HGNC Gene Label(s) | SPRYD3 |
| Structure Name | crystal sturcture of human spry domain |
| Resolution | 2.0Å |
| Reference | AUTH S.KISHISHITA,T.UCHIKUBO-KAMO,K.MURAYAMA,T.TERADA,AUTH 2 L.CHEN,Z.Q.FU,J.CHRZAS,M.SHIROUZU,B.C.WANG,AUTH 3 S.YOKOYAMATITL CRYSTAL STURCTURE OF HUMAN SPRY DOMAINREF TO BE PUBLISHEDREFN |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 155 |
| Number Of SNVs | 14 |
| Number Of Permutations | 1325 |
| Optimal Distance Threshold | 8.0 |
| K Statistic | 0.022 |
| p-value | 0.072 |
COSMIC
| Number Of Residues | 155 |
| Number Of SNVs | 3 |
| Number Of Permutations | 18 |
| Optimal Distance Threshold | 9.0 |
| K Statistic | 0.333 |
| p-value | 0.494 |
Ripley’s K Analysis Plots
ExACCOSMIC


Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 14 |
| Number Of COSMIC SNVs | 3 |
| Optimal Distance Threshold | 9.0 |
| K Statistic | 0.278 |
| p-value | 0.395 |