General Structure Information
| PDB ID | 3gcx |
| HGNC Gene Label(s) | PCSK9 |
| Structure Name | pcsk9:egfa (ph 7.4) |
| Resolution | 2.7Å |
| Reference | AUTH M.C.MCNUTT,H.J.KWON,C.CHEN,J.R.CHEN,J.D.HORTON,T.A.LAGACETITL ANTAGONISM OF SECRETED PCSK9 INCREASES LOW DENSITYTITL 2 LIPOPROTEIN RECEPTOR EXPRESSION IN HEPG2 CELLS.REF J.BIOL.CHEM. V. 284 10561 2009REFN ISSN 0021-9258PMID 19224862DOI 10.1074/JBC.M808802200 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 92 |
| Number Of SNVs | 32 |
| Number Of Permutations | 3490 |
| Optimal Distance Threshold | 12.0 |
| K Statistic | 0.214 |
| p-value | 0.238 |