Assessment of Structural Intolerance and Durability
General Structure Information 2jvz KHSRP solution nmr structure of the second and third kh domains of ksrp -1.0Å AUTH I.DIAZ-MORENO,D.HOLLINGWORTH,M.F.GARCIA-MAYORAL,AUTH 2 G.KELLY,S.MARTIN,C.Y.CHEN,A.RAMOSTITL SOLUTION NMR STRUCTURE OF THE SECOND AND THIRD KHTITL 2 DOMAINS OF KSRPREF TO BE PUBLISHED 2007REFN Variant Set Distributions Mapped Variants
General Structure Information 2nq3 ITCH crystal structure of the c2 domain of human itchy homolog e3 ubiquitin protein ligase 1.8Å AUTH J.R.WALKER,G.V.AVVAKUMOV,S.XUE,C.BUTLER-COLE,AUTH 2 P.J.FINERTY JR.,J.WEIGELT,M.SUNDSTROM,AUTH 3 C.H.ARROWSMITH,A.M.EDWARDS,A.BOCHKAREV,AUTH 4 S.DHE-PAGANONTITL THE C2 DOMAIN OF HUMAN ITCHY HOMOLOG E3 UBIQUITINTITL 2 PROTEIN LIGASEREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 3lcy TTN titin ig tandem domains a164-a165 2.5Å AUTH Q.CHEN,M.WILMANNSTITL STRUCTURAL INVESTIGATION OF THE TITIN A-BAND TANDEM IGTITL 2 DOMAINS A164-A165REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 3ueo TOPBP1 crystal structure of topbp1 brct4/5 domains in complex with a phospho- peptide 2.6Å AUTH C.C.LEUNG,L.SUN,Z.GONG,M.BURKAT,R.EDWARDS,M.ASSMUS,J.CHEN,AUTH 2 J.N.GLOVERTITL STRUCTURAL INSIGHTS INTO RECOGNITION OF MDC1 BY TOPBP1 INTITL 2 DNA REPLICATION CHECKPOINT CONTROL.REF STRUCTURE V. 21 1450 2013REFN ISSN 0969-2126PMID 23891287DOI 10.1016/J.STR.2013.06.015 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons […]
General Structure Information 2ysx INPP5D solution structure of the human ship sh2 domain -1.0Å AUTH T.KASAI,S.KOSHIBA,S.WATANABE,T.HARADA,T.KIGAWA,AUTH 2 S.YOKOYAMATITL SOLUTION STRUCTURE OF THE HUMAN SHIP SH2 DOMAINREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 3tug ITCH crystal structure of the hect domain of itch e3 ubiquitin ligase 2.27Å AUTH E.DOBROVETSKY,A.DONG,S.XUE,C.BUTLER,A.WERNIMONT,J.R.WALKER,AUTH 2 W.TEMPEL,S.DHE-PAGANON,C.H.ARROWSMITH,A.M.EDWARDS,C.BOUNTRA,AUTH 3 Y.TONGTITL CRYSTAL STRUCTURE OF THE HECT DOMAIN OF ITCH E3 UBIQUITINTITL 2 LIGASEREF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 3o3i PIWIL1 crystal structure of human hiwi1 paz domain (residues 277-399) in complex with 14-mer rna (12-bp + 2-nt overhang) containing 2-oh at its 3-end 2.8Å AUTH Y.TIAN,D.K.SIMANSHU,J.B.MA,D.J.PATELTITL INAUGURAL ARTICLE: STRUCTURAL BASIS FOR PIRNATITL 2 2-O-METHYLATED 3-END RECOGNITION BY PIWI PAZTITL 3 (PIWI/ARGONAUTE/ZWILLE) DOMAINS.REF PROC.NATL.ACAD.SCI.USA V. 108 903 2011REFN ISSN 0027-8424PMID 21193640DOI […]
General Structure Information 2uzc PDLIM5 structure of human pdlim5 in complex with the c-terminal peptide of human alpha-actinin-1 1.5Å AUTH J.M.ELKINS,C.GILEADI,L.SHRESTHA,C.PHILLIPS,J.WANG,AUTH 2 J.R.C.MUNIZ,D.A.DOYLETITL UNUSUAL BINDING INTERACTIONS IN PDZ DOMAIN CRYSTALTITL 2 STRUCTURES HELP EXPLAIN BINDING MECHANISMS.REF PROTEIN SCI. V. 19 731 2010REFN ISSN 0961-8368PMID 20120020DOI 10.1002/PRO.349 Variant Set Distributions Mapped Variants
General Structure Information 2izv SOCS4 crystal structure of socs-4 in complex with elongin-b and elongin-c at 2.55a resolution 2.55Å AUTH A.N.BULLOCK,M.C.RODRIGUEZ,J.E.DEBRECZENI,Z.SONGYANG,S.KNAPPTITL STRUCTURE OF THE SOCS4-ELONGINB/C COMPLEX REVEALS ATITL 2 DISTINCT SOCS BOX INTERFACE AND THE MOLECULAR BASIS FORTITL 3 SOCS-DEPENDENT EGFR DEGRADATION.REF STRUCTURE V. 15 1493 2007REFN ISSN 0969-2126PMID 17997974DOI 10.1016/J.STR.2007.09.016 Variant Set Distributions Mapped […]
General Structure Information 2wwm TTN crystal structure of the titin m10-obscurin like 1 ig complex in space group p1 2.3Å AUTH S.PERNIGO,A.FUKUZAWA,M.BERTZ,M.HOLT,M.RIEF,R.A.STEINER,AUTH 2 M.GAUTELTITL STRUCTURAL INSIGHT INTO M-BAND ASSEMBLY AND MECHANICS FROMTITL 2 THE TITIN-OBSCURIN-LIKE-1 COMPLEX.REF PROC.NATL.ACAD.SCI.USA V. 107 2908 2010REFN ISSN 0027-8424PMID 20133654DOI 10.1073/PNAS.0913736107 Variant Set Distributions Pathogenic Proximity Analysis Mapped Variants