General Structure Information
| PDB ID | 2wwm |
| HGNC Gene Label(s) | TTN |
| Structure Name | crystal structure of the titin m10-obscurin like 1 ig complex in space group p1 |
| Resolution | 2.3Å |
| Reference | AUTH S.PERNIGO,A.FUKUZAWA,M.BERTZ,M.HOLT,M.RIEF,R.A.STEINER,AUTH 2 M.GAUTELTITL STRUCTURAL INSIGHT INTO M-BAND ASSEMBLY AND MECHANICS FROMTITL 2 THE TITIN-OBSCURIN-LIKE-1 COMPLEX.REF PROC.NATL.ACAD.SCI.USA V. 107 2908 2010REFN ISSN 0027-8424PMID 20133654DOI 10.1073/PNAS.0913736107 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 99 |
| Number Of SNVs | 25 |
| Number Of Permutations | 3472 |
| Optimal Distance Threshold | 7.0 |
| K Statistic | 0.05 |
| p-value | 0.381 |
ClinVar
| Number Of Residues | 99 |
| Number Of SNVs | 4 |
| Number Of Permutations | 364 |
| Optimal Distance Threshold | 6.0 |
| K Statistic | 0.333 |
| p-value | 0.016 |
Ripley’s K Analysis Plots
ExACClinVar
Variant Set Comparisons
ClinVar vs. ExAC
| Number Of ExAC SNVs | 25 |
| Number Of ClinVar SNVs | 4 |
| Optimal Distance Threshold | 12.0 |
| K Statistic | 0.617 |
| p-value | 0.01 |
Pathogenic Proximity Analysis
ClinVar PathProx Analysis
