Assessment of Structural Intolerance and Durability
General Structure Information 4c9y SKA1 structural basis for the microtubule binding of the human kinetochore ska complex 2.01Å AUTH M.A.ABAD,B.MEDINA,A.SANTAMARIA,J.ZOU,C.PLASBERG-HILL,AUTH 2 A.MADHUMALAR,U.JAYACHANDRAN,P.M.REDLI,J.RAPPSILBER,E.A.NIGG,AUTH 3 A.A.JEYAPRAKASHTITL STRUCTURAL BASIS FOR MICROTUBULE RECOGNITION BY THE HUMANTITL 2 KINETOCHORE SKA COMPLEX.REF NAT.COMMUN. V. 5 2964 2014REFN ISSN 2041-1723PMID 24413531DOI 10.1038/NCOMMS3964 Variant Set Distributions Mapped Variants
General Structure Information 1uit DLG5 solution structure of rsgi ruh-006, the third pdz domain of hdlg5 (kiaa0583) protein [homo sapiens] -1.0Å AUTH T.ABE,H.HIROTA,N.KOBAYASHI,F.HAYASHI,S.YOKOYAMATITL SOLUTION STRUCTURE OF RSGI RUH-006, THE THIRD PDZTITL 2 DOMAIN OF HDLG5 (KIAA0583) PROTEIN [HOMO SAPIENS]REF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis […]
General Structure Information 3fkc ZBTB33 crystal structure of human zinc finger and btb domain containing 33 1.7Å AUTH P.FILIPPAKOPOULOS,A.BULLOCK,T.KEATES,N.BURGESS-BROWN,AUTH 2 J.MUNIZ,F.VON DELFT,C.H.ARROWSMITH,A.M.EDWARDS,J.WEIGELT,AUTH 3 C.BOUNTRA,S.KNAPPTITL CRYSTAL STRUCTURE OF HUMAN ZINC FINGER AND BTB DOMAINTITL 2 CONTAINING 33REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2v90 PDZD3 crystal structure of the 3rd pdz domain of intestine- and kidney-enriched pdz domain ikepp (pdzd3) 2.0Å AUTH J.UPPENBERG,C.GILEADI,C.PHILLIPS,J.ELKINS,G.BUNKOCZI,AUTH 2 C.COOPER,A.C.W.PIKE,E.SALAH,E.UGOCHUKWU,C.H.ARROWSMITH,AUTH 3 A.EDWARDS,M.SUNDSTROM,J.WEIGELT,D.A.DOYLETITL CRYSTAL STRUCTURE OF THE 3RD PDZ DOMAIN OF INTESTINE- ANDTITL 2 KIDNEY-ENRICHED PDZ DOMAIN IKEPP ( PDZD3)REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 4f0d PARP16 human artd15/parp16 in complex with 3-aminobenzamide 2.7Å AUTH T.KARLBERG,A.G.THORSELL,A.KALLAS,H.SCHULERTITL CRYSTAL STRUCTURE OF HUMAN ADP-RIBOSE TRANSFERASETITL 2 ARTD15/PARP16 REVEALS A NOVEL PUTATIVE REGULATORY DOMAIN.REF J.BIOL.CHEM. V. 287 24077 2012REFN ISSN 0021-9258PMID 22661712DOI 10.1074/JBC.M112.379289 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 2db5 INADL solution structure of the first pdz domain of inad-like protein -1.0Å AUTH K.INOUE,C.KUROSAKI,F.HAYASHI,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE FIRST PDZ DOMAIN OFTITL 2 INAD-LIKE PROTEINREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2m38 ANKS1B ptb domain of aida1 -1.0Å AUTH L.DONALDSONTITL TO BE PUBLISHEDREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2epz ZFP28 solution structure of the 4th c2h2 type zinc finger domain of zinc finger protein 28 homolog -1.0Å AUTH K.FUTAMI,S.SUZUKI,Y.MUTO,M.INOUE,T.KIGAWA,T.TERADA,AUTH 2 M.SHIROUZU,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE 4TH C2H2 TYPE ZINCTITL 2 FINGER DOMAIN OF ZINC FINGER PROTEIN 28 HOMOLOGREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2m1x TICAM1 ticam-1 tir domain structure -1.0Å AUTH Y.ENOKIZONO,H.KUMETA,K.FUNAMI,M.HORIUCHI,J.SARMIENTO,AUTH 2 K.YAMASHITA,D.M.STANDLEY,M.MATSUMOTO,T.SEYA,F.INAGAKITITL STRUCTURES AND INTERFACE MAPPING OF THE TIRTITL 2 DOMAIN-CONTAINING ADAPTOR MOLECULES INVOLVED IN INTERFERONTITL 3 SIGNALING.REF PROC.NATL.ACAD.SCI.USA V. 110 19908 2013REFN ISSN 0027-8424PMID 24255114DOI 10.1073/PNAS.1222811110 Variant Set Distributions Mapped Variants
General Structure Information 2ehr INADL solution structure of the sixth pdz domain of human inad- like protein -1.0Å AUTH K.INOUE,F.HAYASHI,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE SIXTH PDZ DOMAIN OFTITL 2 HUMAN INAD-LIKE PROTEINREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants