General Structure Information
| PDB ID | 4f0d |
| HGNC Gene Label(s) | PARP16 |
| Structure Name | human artd15/parp16 in complex with 3-aminobenzamide |
| Resolution | 2.7Å |
| Reference | AUTH T.KARLBERG,A.G.THORSELL,A.KALLAS,H.SCHULERTITL CRYSTAL STRUCTURE OF HUMAN ADP-RIBOSE TRANSFERASETITL 2 ARTD15/PARP16 REVEALS A NOVEL PUTATIVE REGULATORY DOMAIN.REF J.BIOL.CHEM. V. 287 24077 2012REFN ISSN 0021-9258PMID 22661712DOI 10.1074/JBC.M112.379289 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 237 |
| Number Of SNVs | 73 |
| Number Of Permutations | 11124 |
| Optimal Distance Threshold | 15.0 |
| K Statistic | 0.171 |
| p-value | 0.051 |
COSMIC
| Number Of Residues | 237 |
| Number Of SNVs | 4 |
| Number Of Permutations | 43 |
| Optimal Distance Threshold | 15.0 |
| K Statistic | 0.167 |
| p-value | 1.0 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 73 |
| Number Of COSMIC SNVs | 4 |
| Optimal Distance Threshold | 12.0 |
| K Statistic | -0.102 |
| p-value | 0.765 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
