General Structure Information
| PDB ID | 3ueo |
| HGNC Gene Label(s) | TOPBP1 |
| Structure Name | crystal structure of topbp1 brct4/5 domains in complex with a phospho- peptide |
| Resolution | 2.6Å |
| Reference | AUTH C.C.LEUNG,L.SUN,Z.GONG,M.BURKAT,R.EDWARDS,M.ASSMUS,J.CHEN,AUTH 2 J.N.GLOVERTITL STRUCTURAL INSIGHTS INTO RECOGNITION OF MDC1 BY TOPBP1 INTITL 2 DNA REPLICATION CHECKPOINT CONTROL.REF STRUCTURE V. 21 1450 2013REFN ISSN 0969-2126PMID 23891287DOI 10.1016/J.STR.2013.06.015 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 186 |
| Number Of SNVs | 45 |
| Number Of Permutations | 21925 |
| Optimal Distance Threshold | 11.0 |
| K Statistic | 0.097 |
| p-value | 0.226 |
COSMIC
| Number Of Residues | 186 |
| Number Of SNVs | 3 |
| Number Of Permutations | 190 |
| Optimal Distance Threshold | 8.0 |
| K Statistic | 0.333 |
| p-value | 0.599 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
