Assessment of Structural Intolerance and Durability
General Structure Information 2k2o MYOF solution structure of the inner dysf domain of human myoferlin -1.0Å AUTH P.PATEL,R.HARRIS,S.M.GEDDES,E.M.STREHLE,J.D.WATSON,AUTH 2 R.BASHIR,K.BUSHBY,P.C.DRISCOLL,N.H.KEEPTITL SOLUTION STRUCTURE OF THE INNER DYSF DOMAIN OFTITL 2 MYOFERLIN AND IMPLICATIONS FOR LIMB GIRDLETITL 3 MUSCULAR DYSTROPHY TYPE 2B.REF J.MOL.BIOL. V. 379 981 2008REFN ISSN 0022-2836PMID 18495154DOI 10.1016/J.JMB.2008.04.046 Variant Set Distributions Ripley’s K Analysis […]
General Structure Information 1wh1 PDZRN3 solution structure of the fourth pdz domain of kiaa1095 protein -1.0Å AUTH X.QIN,K.SAITO,T.KIGAWA,F.HAYASHI,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE FOURTH PDZ DOMAIN OFTITL 2 KIAA1095 PROTEINREF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped Variants
General Structure Information 4doh IL20RA il20/il201/il20r2 ternary complex 2.8Å AUTH N.J.LOGSDON,A.DESHPANDE,B.D.HARRIS,K.R.RAJASHANKAR,AUTH 2 M.R.WALTERTITL STRUCTURAL BASIS FOR RECEPTOR SHARING AND ACTIVATION BYTITL 2 INTERLEUKIN-20 RECEPTOR-2 (IL-20R2) BINDING CYTOKINES.REF PROC.NATL.ACAD.SCI.USA V. 109 12704 2012REFN ISSN 0027-8424PMID 22802649DOI 10.1073/PNAS.1117551109 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 4doh IL20 il20/il201/il20r2 ternary complex 2.8Å AUTH N.J.LOGSDON,A.DESHPANDE,B.D.HARRIS,K.R.RAJASHANKAR,AUTH 2 M.R.WALTERTITL STRUCTURAL BASIS FOR RECEPTOR SHARING AND ACTIVATION BYTITL 2 INTERLEUKIN-20 RECEPTOR-2 (IL-20R2) BINDING CYTOKINES.REF PROC.NATL.ACAD.SCI.USA V. 109 12704 2012REFN ISSN 0027-8424PMID 22802649DOI 10.1073/PNAS.1117551109 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 3jtc PROCR importance of mg2+ in the ca2+-dependent folding of the gamma- carboxyglutamic acid domains of vitamin k-dependent clotting and anticlotting proteins 1.6Å AUTH K.VADIVEL,S.AGAH,A.S.MESSER,D.CASCIO,M.S.BAJAJ,AUTH 2 S.KRISHNASWAMY,C.T.ESMON,K.PADMANABHAN,S.P.BAJAJTITL STRUCTURAL AND FUNCTIONAL STUDIES OF GAMMA-CARBOXYGLUTAMICTITL 2 ACID DOMAINS OF FACTOR VIIA AND ACTIVATED PROTEIN C: ROLE OFTITL 3 MAGNESIUM AT PHYSIOLOGICAL CALCIUM.REF J.MOL.BIOL. V. […]
General Structure Information 2box EMR2 egf domains 1,2,5 of human emr2, a 7-tm immune system molecule, in complex with strontium. 2.5Å AUTH R.J.M.ABBOTT,I.SPENDLOVE,P.ROVERSI,H.FITZGIBBON,V.KNOTT,AUTH 2 P.TERIETE,J.M.MCDONNELL,P.A.HANDFORD,S.M.LEATITL STRUCTURAL AND FUNCTIONAL CHARACTERIZATION OF A NOVEL TTITL 2 CELL RECEPTOR CO-REGULATORY PROTEIN COMPLEX, CD97-CD55.REF J.BIOL.CHEM. V. 282 22023 2007REFN ISSN 0021-9258PMID 17449467DOI 10.1074/JBC.M702588200 Variant Set Distributions Ripley’s K Analysis […]
General Structure Information 3qnt NPC1L1 npc1l1 (ntd) structure 2.83Å AUTH H.J.KWON,M.PALNITKAR,J.DEISENHOFERTITL THE STRUCTURE OF THE NPC1L1 N-TERMINAL DOMAIN IN A CLOSEDTITL 2 CONFORMATION.REF PLOS ONE V. 6 E1872 2011REFN ESSN 1932-6203PMID 21525977DOI 10.1371/JOURNAL.PONE.0018722 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped Variants
General Structure Information 3qwl TBC1D7 crystal structure of human tbc1 domain family member 7 1.9Å AUTH X.GUAN,W.TEMPEL,Y.TONG,A.K.WERNIMONT,R.LANDRY,AUTH 2 C.H.ARROWSMITH,A.M.EDWARDS,C.BOUNTRA,J.WEIGELT,H.PARKTITL CRYSTAL STRUCTURE OF HUMAN TBC1 DOMAIN FAMILY MEMBER 7REF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped Variants
General Structure Information 3toj ASH2L structure of the spry domain of human ash2l 2.07Å AUTH Y.CHEN,F.CAO,B.WAN,Y.DOU,M.LEITITL STRUCTURE OF THE SPRY DOMAIN OF HUMAN ASH2L AND ITSTITL 2 INTERACTIONS WITH RBBP5 AND DPY30.REF CELL RES. V. 22 598 2012REFN ISSN 1001-0602PMID 22231628DOI 10.1038/CR.2012.9 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped Variants
General Structure Information 1v83 B3GAT1 crystal structure of human glcat-p in complex with udp and mn2+ 1.9Å AUTH S.KAKUDA,T.SHIBA,M.ISHIGURO,H.TAGAWA,S.OKA,AUTH 2 Y.KAJIHARA,T.KAWASAKI,S.WAKATSUKI,R.KATOTITL STRUCTURAL BASIS FOR ACCEPTOR SUBSTRATETITL 2 RECOGNITION OF A HUMAN GLUCURONYLTRANSFERASE,TITL 3 GLCAT-P, AN ENZYME CRITICAL IN THE BIOSYNTHESIS OFTITL 4 THE CARBOHYDRATE EPITOPE HNK-1REF J.BIOL.CHEM. V. 279 22693 2004REFN ISSN 0021-9258PMID 14993226DOI 10.1074/JBC.M400622200 […]