General Structure Information
| PDB ID | 4doh |
| HGNC Gene Label(s) | IL20 |
| Structure Name | il20/il201/il20r2 ternary complex |
| Resolution | 2.8Å |
| Reference | AUTH N.J.LOGSDON,A.DESHPANDE,B.D.HARRIS,K.R.RAJASHANKAR,AUTH 2 M.R.WALTERTITL STRUCTURAL BASIS FOR RECEPTOR SHARING AND ACTIVATION BYTITL 2 INTERLEUKIN-20 RECEPTOR-2 (IL-20R2) BINDING CYTOKINES.REF PROC.NATL.ACAD.SCI.USA V. 109 12704 2012REFN ISSN 0027-8424PMID 22802649DOI 10.1073/PNAS.1117551109 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 152 |
| Number Of SNVs | 47 |
| Number Of Permutations | 12870 |
| Optimal Distance Threshold | 13.0 |
| K Statistic | 0.225 |
| p-value | 0.867 |
COSMIC
| Number Of Residues | 152 |
| Number Of SNVs | 4 |
| Number Of Permutations | 1 |
| Optimal Distance Threshold | 16.0 |
| K Statistic | 0.167 |
| p-value | 1.0 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 47 |
| Number Of COSMIC SNVs | 3 |
| Optimal Distance Threshold | 15.0 |
| K Statistic | -0.298 |
| p-value | 0.464 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
