General Structure Information 3p0u NR2C2 crystal structure of the ligand binding domain of human testicular receptor 4 3.0Å AUTH X.E.ZHOU,K.M.SUINO-POWELL,Y.XU,C.W.CHAN,O.TANABE,S.W.KRUSE,AUTH 2 R.REYNOLDS,J.D.ENGEL,H.E.XUTITL THE ORPHAN NUCLEAR RECEPTOR TR4 IS A VITAMIN A-ACTIVATEDTITL 2 NUCLEAR RECEPTOR.REF J.BIOL.CHEM. V. 286 2877 2011REFN ISSN 0021-9258PMID 21068381DOI 10.1074/JBC.M110.168740 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity […]
General Structure Information 3ii6 LIG4 structure of human xrcc4 in complex with the tandem brct domains of dna ligaseiv. 2.4Å AUTH P.Y.WU,P.FRIT,S.MEESALA,S.DAUVILLIER,M.MODESTI,AUTH 2 S.N.ANDRES,Y.HUANG,J.SEKIGUCHI,P.CALSOU,B.SALLES,AUTH 3 M.S.JUNOPTITL STRUCTURAL AND FUNCTIONAL INTERACTION BETWEEN THETITL 2 HUMAN DNA REPAIR PROTEINS DNA LIGASE IV AND XRCC4REF MOL.CELL.BIOL. V. 11 3163 2009REFN ISSN 0270-7306PMID 19332554 Variant Set Distributions Ripley’s K […]
General Structure Information 1yr5 DAPK1 1.7-a structure of calmodulin bound to a peptide from dap kinase 1.7Å AUTH P.KURSULA,J.VAHOKOSKI,M.WILMANNSTITL RECOGNITION OF HUMAN DEATH-ASSOCIATED PROTEIN KINASES BYTITL 2 CALMODULINREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 1elw STIP1 crystal structure of the tpr1 domain of hop in complex with a hsc70 peptide 1.6Å AUTH C.SCHEUFLER,A.BRINKER,G.BOURENKOV,S.PEGORARO,AUTH 2 L.MORODER,H.BARTUNIK,F.U.HARTL,I.MOAREFITITL STRUCTURE OF TPR DOMAIN-PEPTIDE COMPLEXES:TITL 2 CRITICAL ELEMENTS IN THE ASSEMBLY OF THETITL 3 HSP70-HSP90 MULTICHAPERONE MACHINEREF CELL(CAMBRIDGE,MASS.) V. 101 199 2000REFN ISSN 0092-8674PMID 10786835DOI 10.1016/S0092-8674(00)80830-2 Variant Set Distributions Mapped Variants
General Structure Information 2kk1 ABL2 solution structure of c-terminal domain of tyrosine-protein kinase abl2 from homo sapiens, northeast structural genomics consortium (nesg) target hr5537a -1.0Å AUTH G.LIU,Y.J.HUANG,R.XIAO,D.WANG,T.B.ACTON,AUTH 2 G.T.MONTELIONETITL NMR STRUCTURE OF F-ACTIN-BINDING DOMAIN OF ARG/ABL2TITL 2 FROM HOMO SAPIENS.REF PROTEINS V. 78 1326 2010REFN ISSN 0887-3585PMID 20077570DOI 10.1002/PROT.22656 Variant Set Distributions Mapped Variants
General Structure Information 3uom CASQ1 ca2+ complex of human skeletal calsequestrin 2.02Å AUTH E.J.SANCHEZ,K.M.LEWIS,B.R.DANNA,C.KANGTITL HIGH-CAPACITY CA2+ BINDING OF HUMAN SKELETAL CALSEQUESTRIN.REF J.BIOL.CHEM. V. 287 11592 2012REFN ISSN 0021-9258PMID 22337878DOI 10.1074/JBC.M111.335075 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 3evs GDF5 crystal structure of the gdf-5:bmp receptor ib complex. 2.1Å AUTH A.KOTZSCH,J.NICKEL,A.SEHER,W.SEBALD,T.D.MULLERTITL CRYSTAL STRUCTURE ANALYSIS REVEALS A SPRING-LOADED LATCH ASTITL 2 MOLECULAR MECHANISM FOR GDF-5-TYPE I RECEPTOR SPECIFICITY.REF EMBO J. V. 28 937 2009REFN ISSN 0261-4189PMID 19229295DOI 10.1038/EMBOJ.2009.37 Variant Set Distributions Pathogenic Proximity Analysis Mapped Variants
General Structure Information 3alo MAP2K4 crystal structure of human non-phosphorylated mkk4 kinase domain ternary complex with amp-pnp and p38 peptide 2.6Å AUTH T.MATSUMOTO,T.KINOSHITA,Y.KIRII,K.YOKOTA,K.HAMADA,T.TADATITL CRYSTAL STRUCTURES OF MKK4 KINASE DOMAIN REVEAL THATTITL 2 SUBSTRATE PEPTIDE BINDS TO AN ALLOSTERIC SITE AND INDUCES ANTITL 3 AUTO-INHIBITION STATEREF BIOCHEM.BIOPHYS.RES.COMMUN. V. 400 369 2010REFN ISSN 0006-291XPMID 20732303DOI 10.1016/J.BBRC.2010.08.071 Variant […]
General Structure Information 2pqa RPA3 crystal structure of full-length human rpa 14/32 heterodimer 2.5Å AUTH X.DENG,J.E.HABEL,V.KABALEESWARAN,E.H.SNELL,M.S.WOLD,AUTH 2 G.E.BORGSTAHLTITL STRUCTURE OF THE FULL-LENGTH HUMAN RPA14/32 COMPLEX GIVESTITL 2 INSIGHTS INTO THE MECHANISM OF DNA BINDING AND COMPLEXTITL 3 FORMATION.REF J.MOL.BIOL. V. 374 865 2007REFN ISSN 0022-2836PMID 17976647DOI 10.1016/J.JMB.2007.09.074 Variant Set Distributions Mapped Variants
General Structure Information 1j1d TNNT2 crystal structure of the 46kda domain of human cardiac troponin in the ca2+ saturated form 2.61Å AUTH S.TAKEDA,A.YAMASHITA,K.MAEDA,Y.MAEDATITL STRUCTURE OF THE CORE DOMAIN OF HUMAN CARDIACTITL 2 TROPONIN IN THE CA2+-SATURATED FORMREF NATURE V. 424 35 2003REFN ISSN 0028-0836PMID 12840750DOI 10.1038/NATURE01780 Variant Set Distributions Mapped Variants