Assessment of Structural Intolerance and Durability
General Structure Information 3zyj NTNG1 netring1 in complex with ngl1 3.25Å AUTH E.SEIRADAKE,C.H.COLES,P.V.PERESTENKO,K.HARLOS,AUTH 2 R.A.J.MCILHINNEY,A.R.ARICESCU,E.Y.JONESTITL STRUCTURAL BASIS FOR CELL SURFACE PATTERNINGTITL 2 THROUGH NETRING-NGL INTERACTIONS.REF EMBO J. V. 30 4479 2011REFN ISSN 0261-4189PMID 21946559DOI 10.1038/EMBOJ.2011.346 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 4hlj ROBO1 axon guidance receptor 1.8Å AUTH R.BARAK,Y.OPATOWSKYTITL CRYSTAL STRUCTURE OF AXON GUIDANCE RECEPTORREF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 1nbq F11R crystal structure of human junctional adhesion molecule type 1 2.9Å AUTH A.E.PROTA,J.A.CAMPBELL,P.SCHELLING,J.C.FORREST,AUTH 2 M.J.WATSON,T.R.PETERS,M.AURRAND-LIONS,B.A.IMHOF,AUTH 3 T.S.DERMODY,T.STEHLETITL CRYSTAL STRUCTURE OF HUMAN JUNCTIONAL ADHESIONTITL 2 MOLECULE 1: IMPLICATIONS FOR REOVIRUS BINDINGREF PROC.NATL.ACAD.SCI.USA V. 100 5366 2003REFN ISSN 0027-8424PMID 12697893DOI 10.1073/PNAS.0937718100 Variant Set Distributions Mapped Variants
General Structure Information 2crm FNDC3A solution structure of the forth fniii domain of human -1.0Å AUTH K.IZUMI,F.HAYASHI,M.YOSHIDA,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE FORTH FNIII DOMAIN OFTITL 2 HUMANREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2df3 SIGLEC7 the structure of siglec-7 in complex with alpha(2,3)/alpha(2,6) disialyl lactotetraosyl 2-(trimethylsilyl)ethyl 1.9Å AUTH H.ATTRILL,H.TAKAZAWA,S.WITT,S.KELM,R.ISECKE,R.BROSSMER,AUTH 2 T.ANDO,H.ISHIDA,M.KISO,P.R.CROCKER,D.M.F.VAN AALTENTITL THE STRUCTURE OF SIGLEC-7 IN COMPLEX WITH SIALOSIDES: LEADSTITL 2 FOR RATIONAL STRUCTURE-BASED INHIBITOR DESIGNREF BIOCHEM.J. V. 397 271 2006REFN ISSN 0264-6021PMID 16623661DOI 10.1042/BJ20060103 Variant Set Distributions Ripley’s K Analysis Plots Variant Set […]
General Structure Information 3bin EPB41L3 structure of the dal-1 and tslc1 (372-383) complex 2.3Å AUTH R.D.BUSAM,A.-G.THORSELL,A.FLORES,M.HAMMARSTROM,C.PERSSON,AUTH 2 B.OBRINK,B.M.HALLBERGTITL STRUCTURAL BASIS OF TUMOR SUPPRESSOR IN LUNG CANCER 1TITL 2 (TSLC1) BINDING TO DIFFERENTIALLY EXPRESSED INTITL 3 ADENOCARCINOMA OF THE LUNG (DAL-1/4.1B)REF J.BIOL.CHEM. V. 286 4511 2011REFN ISSN 0021-9258PMID 21131357DOI 10.1074/JBC.M110.174011 Variant Set Distributions Ripley’s K Analysis […]
General Structure Information 3g5c ADAM22 structural and biochemical studies on the ectodomain of human adam22 2.36Å AUTH H.LIU,A.SHIM,X.CHEN,X.HETITL STRUCTURAL AND BIOCHEMICAL STUDIES ON THE ECTODOMAIN OFTITL 2 HUMAN ADAM22REF J.BIOL.CHEM. 2009REFN ESSN 1083-351X Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped Variants
General Structure Information 3bn3 ICAM5 crystal structure of icam-5 in complex with al i domain 2.1Å AUTH H.ZHANG,J.M.CASASNOVAS,M.JIN,J.H.LIU,C.G.GAHMBERG,AUTH 2 T.A.SPRINGER,J.-H.WANGTITL AN UNUSUAL ALLOSTERIC MOBILITY OF THE C-TERMINAL HELIX OF ATITL 2 HIGH-AFFINITY ALPHA L INTEGRIN I DOMAIN VARIANT BOUND TOTITL 3 ICAM-5REF MOL.CELL V. 31 432 2008REFN ISSN 1097-2765PMID 18691975DOI 10.1016/J.MOLCEL.2008.06.022 Variant Set Distributions Mapped […]
General Structure Information 2osg TJP2 solution structure and binding property of the domain- swapped dimer of zo2pdz2 -1.0Å AUTH J.W.WU,Y.S.YANG,J.H.ZHANG,P.JI,W.J.DU,P.JIANG,AUTH 2 D.H.XIE,H.D.HUANG,M.WU,G.Z.ZHANG,J.H.WU,Y.Y.SHITITL DOMAIN-SWAPPED DIMERIZATION OF THE SECOND PDZTITL 2 DOMAIN OF ZO2 MAY PROVIDE A STRUCTURAL BASIS FORTITL 3 THE POLYMERIZATION OF CLAUDINSREF J.BIOL.CHEM. V. 282 35988 2007REFN ISSN 0021-9258PMID 17897942DOI 10.1074/JBC.M703826200 Variant Set Distributions […]
General Structure Information 2box EMR2 egf domains 1,2,5 of human emr2, a 7-tm immune system molecule, in complex with strontium. 2.5Å AUTH R.J.M.ABBOTT,I.SPENDLOVE,P.ROVERSI,H.FITZGIBBON,V.KNOTT,AUTH 2 P.TERIETE,J.M.MCDONNELL,P.A.HANDFORD,S.M.LEATITL STRUCTURAL AND FUNCTIONAL CHARACTERIZATION OF A NOVEL TTITL 2 CELL RECEPTOR CO-REGULATORY PROTEIN COMPLEX, CD97-CD55.REF J.BIOL.CHEM. V. 282 22023 2007REFN ISSN 0021-9258PMID 17449467DOI 10.1074/JBC.M702588200 Variant Set Distributions Ripley’s K Analysis […]