Assessment of Structural Intolerance and Durability
General Structure Information 2xqn TES complex of the 2nd and 3rd lim domains of tes with the evh1 domain of mena and the n-terminal domain of actin-like protein arp7a 2.62Å AUTH B.BOEDA,P.P.KNOWLES,D.C.BRIGGS,J.MURRAY-RUST,E.SORIANO,AUTH 2 B.K.GARVALOV,N.Q.MCDONALD,M.WAYTITL MOLECULAR RECOGNITION OF THE TES LIM2-3 DOMAINS BY THETITL 2 ACTIN-RELATED PROTEIN ARP7A.REF J.BIOL.CHEM. V. 286 11543 2011REFN ISSN 0021-9258PMID 21278383DOI […]
General Structure Information 2os6 ARHGEF12 solution structure of larg pdz domain in complex with c- terminal octa-peptide of plexin b1 -1.0Å AUTH J.LIU,H.HUANG,Y.YANGTITL SOLUTION STRUCTURE OF THE LARG PDZ DOMAIN INTITL 2 COMPLEX WITH C-TERMINAL PEPTIDE OF PLEXIN B1REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 1v5j IGSF9 solution structure of rsgi ruh-008, fn3 domain in human cdna -1.0Å AUTH Y.DOI-KATAYAMA,F.HAYASHI,H.HIROTA,S.YOKOYAMATITL SOLUTION STRUCTURE OF RSGI RUH-008, A FN3 DOMAINTITL 2 IN HUMAN CDNAREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 3zyj LRRC4C netring1 in complex with ngl1 3.25Å AUTH E.SEIRADAKE,C.H.COLES,P.V.PERESTENKO,K.HARLOS,AUTH 2 R.A.J.MCILHINNEY,A.R.ARICESCU,E.Y.JONESTITL STRUCTURAL BASIS FOR CELL SURFACE PATTERNINGTITL 2 THROUGH NETRING-NGL INTERACTIONS.REF EMBO J. V. 30 4479 2011REFN ISSN 0261-4189PMID 21946559DOI 10.1038/EMBOJ.2011.346 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 2edj ROBO2 solution structure of the fifth ig-like domain from human roundabout homolog 2 -1.0Å AUTH C.KUROSAKI,K.IZUMI,M.YOSHIDA,F.HAYASHI,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE FIFTH IG-LIKE DOMAINTITL 2 FROM HUMAN ROUNDABOUT HOMOLOG 2REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 3zyi LRRC4 netring2 in complex with ngl2 2.6Å AUTH E.SEIRADAKE,C.H.COLES,P.V.PERESTENKO,K.HARLOS,AUTH 2 R.A.J.MCILHINNEY,A.R.ARICESCU,E.Y.JONESTITL STRUCTURAL BASIS FOR CELL SURFACE PATTERNING THROUGHTITL 2 NETRING-NGL INTERACTIONSREF EMBO J. V. 30 4479 2011REFN ISSN 0261-4189PMID 21946559DOI 10.1038/EMBOJ.2011.346 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 4fom PVRL3 crystal structure of human nectin-3 full ectodomain (d1-d3) 3.93Å AUTH O.J.HARRISON,J.VENDOME,J.BRASCH,X.JIN,S.HONG,P.S.KATSAMBA,AUTH 2 G.AHLSEN,R.B.TROYANOVSKY,S.M.TROYANOVSKY,B.HONIG,L.SHAPIROTITL NECTIN ECTODOMAIN STRUCTURES REVEAL A CANONICAL ADHESIVETITL 2 INTERFACE.REF NAT.STRUCT.MOL.BIOL. V. 19 906 2012REFN ISSN 1545-9993PMID 22902367DOI 10.1038/NSMB.2366 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 2gi7 GP6 crystal structure of human platelet glycoprotein vi (gpvi) 2.4Å AUTH K.HORII,M.L.KAHN,A.B.HERRTITL STRUCTURAL BASIS FOR PLATELET COLLAGEN RESPONSES BY THETITL 2 IMMUNE-TYPE RECEPTOR GLYCOPROTEIN VI.REF BLOOD V. 108 936 2006REFN ISSN 0006-4971PMID 16861347DOI 10.1182/BLOOD-2006-01-010215 Variant Set Distributions Mapped Variants
General Structure Information 4kt1 LGR4 complex of r-spondin 1 with lgr4 extracellular domain 2.5Å AUTH D.L.WANG,B.HUANG,S.ZHANG,X.YU,W.WU,X.Q.WANGTITL STRUCTURAL BASIS FOR R-SPONDIN RECOGNITION BY LGR4/5/6TITL 2 RECEPTORSREF GENES DEV. V. 27 1339 2013REFN ISSN 0890-9369PMID 23756652DOI 10.1101/GAD.219360.113 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 4h5s CADM1 complex structure of necl-2 and crtam 1.7Å AUTH S.ZHANG,G.LU,J.QI,Y.LI,Z.ZHANG,B.ZHANG,Z.FAN,J.YAN,G.F.GAOTITL COMPETITION OF CELL ADHESION AND IMMUNE RECOGNITION:TITL 2 INSIGHTS INTO THE INTERACTION BETWEEN CRTAM AND NECTIN-LIKETITL 3 2REF STRUCTURE V. 21 2013REFN ISSN 0969-2126PMID 23871486DOI 10.1016/J.STR.2013.06.006 Variant Set Distributions Mapped Variants