General Structure Information
| PDB ID | 3zyj |
| HGNC Gene Label(s) | LRRC4C |
| Structure Name | netring1 in complex with ngl1 |
| Resolution | 3.25Å |
| Reference | AUTH E.SEIRADAKE,C.H.COLES,P.V.PERESTENKO,K.HARLOS,AUTH 2 R.A.J.MCILHINNEY,A.R.ARICESCU,E.Y.JONESTITL STRUCTURAL BASIS FOR CELL SURFACE PATTERNINGTITL 2 THROUGH NETRING-NGL INTERACTIONS.REF EMBO J. V. 30 4479 2011REFN ISSN 0261-4189PMID 21946559DOI 10.1038/EMBOJ.2011.346 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 396 |
| Number Of SNVs | 60 |
| Number Of Permutations | 47788 |
| Optimal Distance Threshold | 11.0 |
| K Statistic | 0.045 |
| p-value | 0.791 |
COSMIC
| Number Of Residues | 396 |
| Number Of SNVs | 16 |
| Number Of Permutations | 20282 |
| Optimal Distance Threshold | 13.0 |
| K Statistic | 0.033 |
| p-value | 0.981 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 60 |
| Number Of COSMIC SNVs | 8 |
| Optimal Distance Threshold | 34.0 |
| K Statistic | 0.335 |
| p-value | 0.177 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
