2C5L.D | PLCE1

General Structure Information 2c5l PLCE1 structure of plc epsilon ras association domain with hras 1.9Å AUTH T.D.BUNNEY,R.HARRIS,N.L.GANDARILLAS,M.B.JOSEPHS,AUTH 2 S.M.ROE,S.C.SORLI,H.F.PATERSON,F.RODRIGUES-LIMA,AUTH 3 D.ESPOSITO,C.P.PONTING,P.GIESCHIK,L.H.PEARL,AUTH 4 P.C.DRISCOLL,M.KATANTITL STRUCTURAL AND MECHANISTIC INSIGHTS INTO RASTITL 2 ASSOCIATION DOMAINS OF PHOSPHOLIPASE C EPSILONREF MOL.CELL V. 21 495 2006REFN ISSN 1097-2765PMID 16483931DOI 10.1016/J.MOLCEL.2006.01.008 Variant Set Distributions Mapped Variants

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1WI3.A | SATB2

General Structure Information 1wi3 SATB2 solution structure of the homeodomain of kiaa1034 protein -1.0Å AUTH K.IZUMI,M.YOSHIDA,F.HAYASHI,R.HATTA,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE HOMEODOMAIN OF KIAA1034TITL 2 PROTEINREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants

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1PJA.A | PPT2

General Structure Information 1pja PPT2 the crystal structure of palmitoyl protein thioesterase-2 reveals the basis for divergent substrate specificities of the two lysosomal thioesterases (ppt1 and ppt2) 2.7Å AUTH G.CALERO,P.GUPTA,M.C.NONATO,S.TANDEL,E.R.BIEHL,S.L.HOFMANN,AUTH 2 J.CLARDYTITL THE CRYSTAL STRUCTURE OF PALMITOYL PROTEIN THIOESTERASE-2TITL 2 (PPT2) REVEALS THE BASIS FOR DIVERGENT SUBSTRATETITL 3 SPECIFICITIES OF THE TWO LYSOSOMAL THIOESTERASES, PPT1 […]

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2CSF.A | SATB2

General Structure Information 2csf SATB2 solution structure of the second cut domain of human satb2 -1.0Å AUTH K.INOUE,F.HAYASHI,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE SECOND CUT DOMAIN OFTITL 2 HUMAN SATB2REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants

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3TG5.A | SMYD2

General Structure Information 3tg5 SMYD2 structure of smyd2 in complex with p53 and sah 2.3Å AUTH L.WANG,L.LI,H.ZHANG,X.LUO,J.DAI,S.ZHOU,J.GU,J.ZHU,P.ATADJA,AUTH 2 C.LU,E.LI,K.ZHAOTITL STRUCTURE OF HUMAN SMYD2 REVEALS THE BASIS OF P53 TUMORTITL 2 SUPPRESSOR METHYLATIONREF J.BIOL.CHEM. 2011REFN ESSN 1083-351XPMID 21880715DOI 10.1074/JBC.M111.262410 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants

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3MOP.H | IRAK4

General Structure Information 3mop IRAK4 the ternary death domain complex of myd88, irak4, and irak2 3.4Å AUTH S.C.LIN,Y.C.LO,H.WUTITL HELICAL ASSEMBLY IN THE MYD88-IRAK4-IRAK2 COMPLEX INTITL 2 TLR/IL-1R SIGNALLING.REF NATURE V. 465 885 2010REFN ISSN 0028-0836PMID 20485341DOI 10.1038/NATURE09121 Variant Set Distributions Mapped Variants

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2M3D.A | DDX21

General Structure Information 2m3d DDX21 nmr structure of the guct domain from human dead box polypeptide 21 -1.0Å AUTH S.K.DUTTA,P.SERRANO,M.GERALT,K.WUTHRICHTITL NMR STRUCTURE OF THE GUCT DOMAIN FROM HUMAN DEAD BOXTITL 2 POLYPEPTIDE 21 (DDX21)REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants

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3ZYJ.A | LRRC4C

General Structure Information 3zyj LRRC4C netring1 in complex with ngl1 3.25Å AUTH E.SEIRADAKE,C.H.COLES,P.V.PERESTENKO,K.HARLOS,AUTH 2 R.A.J.MCILHINNEY,A.R.ARICESCU,E.Y.JONESTITL STRUCTURAL BASIS FOR CELL SURFACE PATTERNINGTITL 2 THROUGH NETRING-NGL INTERACTIONS.REF EMBO J. V. 30 4479 2011REFN ISSN 0261-4189PMID 21946559DOI 10.1038/EMBOJ.2011.346 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants

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3NWN.A | KIF9

General Structure Information 3nwn KIF9 crystal structure of the human kif9 motor domain in complex with adp 2.0Å AUTH H.ZHU,W.TEMPEL,H.HE,Y.SHEN,J.WANG,G.BROTHERS,R.LANDRY,AUTH 2 C.H.ARROWSMITH,A.M.EDWARDS,M.SUNDSTROM,J.WEIGELT,AUTH 3 A.BOCHKAREV,H.PARKTITL CRYSTAL STRUCTURE OF THE HUMAN KIF9 MOTOR DOMAIN IN COMPLEXTITL 2 WITH ADPREF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants

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2A8J.A | TASP1

General Structure Information 2a8j TASP1 crystal structure of human taspase1 (acivated form) 1.9Å AUTH J.A.KHAN,B.M.DUNN,L.TONGTITL CRYSTAL STRUCTURE OF HUMAN TASPASE1, A CRUCIALTITL 2 PROTEASE REGULATING THE FUNCTION OF MLL.REF STRUCTURE V. 13 1443 2005REFN ISSN 0969-2126PMID 16216576DOI 10.1016/J.STR.2005.07.006 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants

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