Assessment of Structural Intolerance and Durability
General Structure Information 2err RBFOX1 nmr structure of the rna binding domain of human fox-1 in complex with ugcaugu -1.0Å AUTH S.D.AUWETER,R.FASAN,L.REYMOND,J.G.UNDERWOOD,AUTH 2 D.L.BLACK,S.PITSCH,F.H.ALLAINTITL MOLECULAR BASIS OF RNA RECOGNITION BY THE HUMANTITL 2 ALTERNATIVE SPLICING FACTOR FOX-1.REF EMBO J. V. 25 163 2006REFN ISSN 0261-4189PMID 16362037DOI 10.1038/SJ.EMBOJ.7600918 Variant Set Distributions Ripley’s K Analysis Plots Variant […]
General Structure Information 4c9b CWC22 crystal structure of eif4aiii-cwc22 complex 2.0Å AUTH G.BUCHWALD,S.SCHUESSLER,C.BASQUIN,H.LE HIR,E.CONTITITL CRYSTAL STRUCTURE OF THE HUMAN EIF4AIII-CWC22 COMPLEX SHOWSTITL 2 HOW A DEAD-BOX PROTEIN IS INHIBITED BY A MIF4G DOMAINREF PROC.NATL.ACAD.SCI.USA V. 110 E4611 2013REFN ISSN 0027-8424PMID 24218557DOI 10.1073/PNAS.1314684110 Variant Set Distributions Mapped Variants
General Structure Information 3nhb ABCB6 nucleotide binding domain of human abcb6 (adp bound structure) 2.15Å AUTH M.HAFFKE,A.MENZEL,Y.CARIUS,D.JAHN,D.W.HEINZTITL STRUCTURES OF THE NUCLEOTIDE-BINDING DOMAIN OF THE HUMANTITL 2 ABCB6 TRANSPORTER AND ITS COMPLEXES WITH NUCLEOTIDES.REF ACTA CRYSTALLOGR.,SECT.D V. 66 979 2010REFN ISSN 0907-4449PMID 20823549DOI 10.1107/S0907444910028593 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity […]
General Structure Information 4a27 VAT1L crystal structure of human synaptic vesicle membrane protein vat-1 homolog-like protein 2.1Å AUTH M.VOLLMAR,N.SHAFQAT,J.R.C.MUNIZ,T.KROJER,C.ALLERSTON,AUTH 2 F.VON DELFT,C.BOUNTRA,C.H.ARROWSMITH,J.WEIGELT,A.EDWARDS,AUTH 3 W.W.YUE,U.OPPERMANNTITL CRYSTAL STRUCTURE OF HUMAN SYNAPTIC VESICLE MEMBRANETITL 2 PROTEIN VAT-1 HOMOLOG-LIKE PROTEINREF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 2kt0 NANOG solution structure of human stem cell transcription factor nanog homeodomain fragment -1.0Å AUTH S.C.SAHU,J.L.MARKLEYTITL SOLUTION STRUCTURE OF HUMAN STEM CELL TRANSCRIPTION FACTORTITL 2 NANOGREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 3llu RRAGC crystal structure of the nucleotide-binding domain of ras- related gtp-binding protein c 1.4Å AUTH L.NEDYALKOVA,W.TEMPEL,Y.TONG,L.CROMBET,N.ZHONG,AUTH 2 X.GUAN,C.H.ARROWSMITH,A.M.EDWARDS,C.BOUNTRA,AUTH 3 J.WEIGELT,A.BOCHKAREV,H.PARKTITL CRYSTAL STRUCTURE OF THE NUCLEOTIDE-BINDING DOMAINTITL 2 OF RAS-RELATED GTP-BINDING PROTEIN CREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 3au5 MYO10 structure of the human myosin-x myth4-ferm cassette 2.55Å AUTH Y.HIRANO,T.HATANO,A.TAKAHASHI,M.TORIYAMA,N.INAGAKI,AUTH 2 T.HAKOSHIMATITL STRUCTURAL BASIS OF CARGO RECOGNITION BY THE MYOSIN-XTITL 2 MYTH4-FERM DOMAINREF EMBO J. V. 30 2734 2011REFN ISSN 0261-4189PMID 21642953DOI 10.1038/EMBOJ.2011.177 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 2jq6 EHD1 structure of eh-domain of ehd1 -1.0Å AUTH F.KIEKEN,M.JOVIC,N.NASLAVSKY,S.CAPLAN,P.L.SORGENTITL EH DOMAIN OF EHD1REF J.BIOMOL.NMR V. 39 323 2007REFN ISSN 0925-2738PMID 17899392DOI 10.1007/S10858-007-9196-0 Variant Set Distributions Mapped Variants
General Structure Information 4fo0 ACTR8 human actin-related protein arp8 in its atp-bound state 2.6Å AUTH C.B.GERHOLD,D.D.WINKLER,K.LAKOMEK,F.U.SEIFERT,S.FENN,AUTH 2 B.KESSLER,G.WITTE,K.LUGER,K.P.HOPFNERTITL STRUCTURE OF ACTIN-RELATED PROTEIN 8 AND ITS CONTRIBUTION TOTITL 2 NUCLEOSOME BINDING.REF NUCLEIC ACIDS RES. V. 40 11036 2012REFN ISSN 0305-1048PMID 22977180DOI 10.1093/NAR/GKS842 Variant Set Distributions Mapped Variants
General Structure Information 2ds4 TRIM45 solution structure of the filamin domain from human tripartite motif protein 45 -1.0Å AUTH T.TOMIZAWA,S.KOSHIBA,S.WATANABE,T.HARADA,T.KIGAWA,AUTH 2 S.YOKOYAMATITL SOLUTION STRUCTURE OF THE FILAMIN DOMAIN FROMTITL 2 HUMAN TRIPARTITE MOTIF PROTEIN 45REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants