General Structure Information
| PDB ID | 4a27 |
| HGNC Gene Label(s) | VAT1L |
| Structure Name | crystal structure of human synaptic vesicle membrane protein vat-1 homolog-like protein |
| Resolution | 2.1Å |
| Reference | AUTH M.VOLLMAR,N.SHAFQAT,J.R.C.MUNIZ,T.KROJER,C.ALLERSTON,AUTH 2 F.VON DELFT,C.BOUNTRA,C.H.ARROWSMITH,J.WEIGELT,A.EDWARDS,AUTH 3 W.W.YUE,U.OPPERMANNTITL CRYSTAL STRUCTURE OF HUMAN SYNAPTIC VESICLE MEMBRANETITL 2 PROTEIN VAT-1 HOMOLOG-LIKE PROTEINREF TO BE PUBLISHEDREFN |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 308 |
| Number Of SNVs | 85 |
| Number Of Permutations | 12748 |
| Optimal Distance Threshold | 8.0 |
| K Statistic | 0.035 |
| p-value | 0.995 |
COSMIC
| Number Of Residues | 308 |
| Number Of SNVs | 9 |
| Number Of Permutations | 1373 |
| Optimal Distance Threshold | 11.0 |
| K Statistic | 0.056 |
| p-value | 0.966 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 85 |
| Number Of COSMIC SNVs | 8 |
| Optimal Distance Threshold | 9.0 |
| K Statistic | -0.043 |
| p-value | 1.0 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
