General Structure Information
| PDB ID | 3tg5 |
| HGNC Gene Label(s) | SMYD2 |
| Structure Name | structure of smyd2 in complex with p53 and sah |
| Resolution | 2.3Å |
| Reference | AUTH L.WANG,L.LI,H.ZHANG,X.LUO,J.DAI,S.ZHOU,J.GU,J.ZHU,P.ATADJA,AUTH 2 C.LU,E.LI,K.ZHAOTITL STRUCTURE OF HUMAN SMYD2 REVEALS THE BASIS OF P53 TUMORTITL 2 SUPPRESSOR METHYLATIONREF J.BIOL.CHEM. 2011REFN ESSN 1083-351XPMID 21880715DOI 10.1074/JBC.M111.262410 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 425 |
| Number Of SNVs | 100 |
| Number Of Permutations | 44509 |
| Optimal Distance Threshold | 20.0 |
| K Statistic | 0.204 |
| p-value | 0.101 |
COSMIC
| Number Of Residues | 425 |
| Number Of SNVs | 5 |
| Number Of Permutations | 705 |
| Optimal Distance Threshold | 17.0 |
| K Statistic | 0.1 |
| p-value | 0.959 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 100 |
| Number Of COSMIC SNVs | 5 |
| Optimal Distance Threshold | 12.0 |
| K Statistic | -0.06 |
| p-value | 0.945 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
