General Structure Information
| PDB ID | 2a8j |
| HGNC Gene Label(s) | TASP1 |
| Structure Name | crystal structure of human taspase1 (acivated form) |
| Resolution | 1.9Å |
| Reference | AUTH J.A.KHAN,B.M.DUNN,L.TONGTITL CRYSTAL STRUCTURE OF HUMAN TASPASE1, A CRUCIALTITL 2 PROTEASE REGULATING THE FUNCTION OF MLL.REF STRUCTURE V. 13 1443 2005REFN ISSN 0969-2126PMID 16216576DOI 10.1016/J.STR.2005.07.006 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 310 |
| Number Of SNVs | 44 |
| Number Of Permutations | 22514 |
| Optimal Distance Threshold | 12.0 |
| K Statistic | 0.134 |
| p-value | 0.264 |
COSMIC
| Number Of Residues | 310 |
| Number Of SNVs | 5 |
| Number Of Permutations | 587 |
| Optimal Distance Threshold | 18.0 |
| K Statistic | 0.1 |
| p-value | 0.65 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 44 |
| Number Of COSMIC SNVs | 5 |
| Optimal Distance Threshold | 18.0 |
| K Statistic | -0.223 |
| p-value | 0.562 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
