Assessment of Structural Intolerance and Durability
General Structure Information 1x6f ZNF462 solution structures of the c2h2 type zinc finger domain of human zinc finger protein 462 -1.0Å AUTH M.SATO,K.SAITO,S.KOSHIBA,M.INOUE,T.KIGAWA,AUTH 2 S.YOKOYAMATITL SOLUTION STRUCTURES OF THE C2H2 TYPE ZINC FINGERTITL 2 DOMAIN OF HUMAN ZINC FINGER PROTEIN 462REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2l80 USP13 solution structure of the zinc finger domain of usp13 -1.0Å AUTH Y.ZHANG,A.SONG,C.ZHOU,Z.ZHOU,H.HUTITL BIOCHEMICAL CHARACTERIZATION OF THE UBIQUITIN RECEPTORS INTITL 2 USP13 REVEALS DIFFERENT CATALYTIC ACTIVATION OFTITL 3 DEUBIQUITINATION FROM ITS ANALOGUE USP5REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 3ddt TRIM63 crystal structure of the b2 box from murf1 in dimeric state 1.9Å AUTH M.MROSEK,S.MEIER,Z.UCURUM-FOTIADIS,E.VON CASTELMUR,AUTH 2 E.HEDBOM,A.LUSTIG,S.GRZESIEK,D.LABEIT,S.LABEIT,AUTH 3 O.MAYANSTITL STRUCTURAL ANALYSIS OF B-BOX 2 FROM MURF1:TITL 2 IDENTIFICATION OF A NOVEL SELF-ASSOCIATION PATTERNTITL 3 IN A RING-LIKE FOLDREF BIOCHEMISTRY V. 47 10722 2008REFN ISSN 0006-2960PMID 18795805DOI 10.1021/BI800733Z Variant Set Distributions […]
General Structure Information 2r02 PDCD6IP crystal structure of alix/aip1 in complex with the hiv-1 ypltsl late domain 2.6Å AUTH Q.ZHAI,R.D.FISHER,H.Y.CHUNG,D.G.MYSZKA,AUTH 2 W.I.SUNDQUIST,C.P.HILLTITL STRUCTURAL AND FUNCTIONAL STUDIES OF ALIXTITL 2 INTERACTIONS WITH YPX(N)L LATE DOMAINS OF HIV-1TITL 3 AND EIAV.REF NAT.STRUCT.MOL.BIOL. V. 15 43 2008REFN ISSN 1545-9993PMID 18066081DOI 10.1038/NSMB1319 Variant Set Distributions Ripley’s K Analysis Plots […]
General Structure Information 4ljq RNF31 crystal structure of the catalytic core of e3 ligase hoip 2.45Å AUTH B.STIEGLITZ,R.R.RANA,M.G.KOLIOPOULOS,A.C.MORRIS-DAVIES,AUTH 2 V.SCHAEFFER,E.CHRISTODOULOU,S.HOWELL,N.R.BROWN,I.DIKIC,AUTH 3 K.RITTINGERTITL STRUCTURAL BASIS FOR LIGASE-SPECIFIC CONJUGATION OF LINEARTITL 2 UBIQUITIN CHAINS BY HOIP.REF NATURE V. 503 422 2013REFN ISSN 0028-0836PMID 24141947DOI 10.1038/NATURE12638 Variant Set Distributions Mapped Variants
General Structure Information 1lt8 BHMT reduced homo sapiens betaine-homocysteine s- methyltransferase in complex with s-(delta-carboxybutyl)-l- homocysteine 2.05Å AUTH J.C.EVANS,D.P.HUDDLER,J.JIRACEK,C.CASTRO,AUTH 2 N.S.MILLIAN,T.A.GARROW,M.L.LUDWIGTITL BETAINE-HOMOCYSTEINE METHYLTRANSFERASE: ZINC IN ATITL 2 DISTORTED BARREL.REF STRUCTURE V. 10 1159 2002REFN ISSN 0969-2126PMID 12220488DOI 10.1016/S0969-2126(02)00796-7 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped Variants
General Structure Information 3fdw SYTL4 crystal structure of a c2 domain from human synaptotagmin- like protein 4 2.2Å AUTH J.B.BONANNO,M.RUTTER,K.T.BAIN,S.MILLER,R.ROMERO,AUTH 2 S.WASSERMAN,J.M.SAUDER,S.K.BURLEY,S.C.ALMOTITL CRYSTAL STRUCTURE OF A C2 DOMAIN FROM HUMANTITL 2 SYNAPTOTAGMIN-LIKE PROTEIN 4REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 1x4v ZFAND2B solution structure of the zf-an1 domain from human hypothetical protein loc130617 -1.0Å AUTH T.TOMIZAWA,T.KIGAWA,S.KOSHIBA,M.INOUE,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE ZF-AN1 DOMAIN FROM HUMANTITL 2 HYPOTHETICAL PROTEIN LOC130617REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 3dqv CUL5 structural insights into nedd8 activation of cullin-ring ligases: conformational control of conjugation 3.0Å AUTH D.M.DUDA,L.A.BORG,D.C.SCOTT,H.W.HUNT,M.HAMMEL,AUTH 2 B.A.SCHULMANTITL STRUCTURAL INSIGHTS INTO NEDD8 ACTIVATION OFTITL 2 CULLIN-RING LIGASES: CONFORMATIONAL CONTROL OFTITL 3 CONJUGATION.REF CELL(CAMBRIDGE,MASS.) V. 134 995 2008REFN ISSN 0092-8674PMID 18805092DOI 10.1016/J.CELL.2008.07.022 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons […]
General Structure Information 3f7g BIRC7 structure of the bir domain from ml-iap bound to a peptidomimetic 2.3Å AUTH F.COHEN,B.ALICKE,L.O.ELLIOTT,J.A.FLYGARE,T.GONCHAROV,AUTH 2 S.F.KETELTAS,M.C.FRANKLIN,S.FRANKOVITZ,J.P.STEPHAN,V.TSUI,AUTH 3 D.VUCIC,H.WONG,W.J.FAIRBROTHERTITL ORALLY BIOAVAILABLE ANTAGONISTS OF INHIBITOR OF APOPTOSISTITL 2 PROTEINS BASED ON AN AZABICYCLOOCTANE SCAFFOLDREF J.MED.CHEM. V. 52 1723 2009REFN ISSN 0022-2623PMID 19228017DOI 10.1021/JM801450C Variant Set Distributions Mapped Variants