General Structure Information 2ce8 TLE1 an eh1 peptide bound to the groucho-tle wd40 domain. 2.03Å AUTH B.H.JENNINGS,L.M.PICKLES,S.M.WAINWRIGHT,S.M.ROE,L.H.PEARL,AUTH 2 D.ISH-HOROWICZTITL MOLECULAR RECOGNITION OF TRANSCRIPTIONAL REPRESSOR MOTIFSTITL 2 BY THE WD DOMAIN OF THE GROUCHO/TLE COREPRESSOR.REF MOL.CELL V. 22 645 2006REFN ISSN 1097-2765PMID 16762837DOI 10.1016/J.MOLCEL.2006.04.024 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity […]
General Structure Information 4my2 NDP crystal structure of norrin in fusion with maltose binding protein 2.4Å AUTH J.KE,K.G.HARIKUMAR,C.ERICE,C.CHEN,X.GU,L.WANG,N.PARKER,AUTH 2 Z.CHENG,W.XU,B.O.WILLIAMS,K.MELCHER,L.J.MILLER,H.E.XUTITL STRUCTURE AND FUNCTION OF NORRIN IN ASSEMBLY AND ACTIVATIONTITL 2 OF A FRIZZLED 4-LRP5/6 COMPLEX.REF GENES DEV. V. 27 2305 2013REFN ISSN 0890-9369PMID 24186977DOI 10.1101/GAD.228544.113 Variant Set Distributions Pathogenic Proximity Analysis Mapped Variants
General Structure Information 2ce8 TLE1 an eh1 peptide bound to the groucho-tle wd40 domain. 2.03Å AUTH B.H.JENNINGS,L.M.PICKLES,S.M.WAINWRIGHT,S.M.ROE,L.H.PEARL,AUTH 2 D.ISH-HOROWICZTITL MOLECULAR RECOGNITION OF TRANSCRIPTIONAL REPRESSOR MOTIFSTITL 2 BY THE WD DOMAIN OF THE GROUCHO/TLE COREPRESSOR.REF MOL.CELL V. 22 645 2006REFN ISSN 1097-2765PMID 16762837DOI 10.1016/J.MOLCEL.2006.04.024 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity […]
General Structure Information 4my2 NDP crystal structure of norrin in fusion with maltose binding protein 2.4Å AUTH J.KE,K.G.HARIKUMAR,C.ERICE,C.CHEN,X.GU,L.WANG,N.PARKER,AUTH 2 Z.CHENG,W.XU,B.O.WILLIAMS,K.MELCHER,L.J.MILLER,H.E.XUTITL STRUCTURE AND FUNCTION OF NORRIN IN ASSEMBLY AND ACTIVATIONTITL 2 OF A FRIZZLED 4-LRP5/6 COMPLEX.REF GENES DEV. V. 27 2305 2013REFN ISSN 0890-9369PMID 24186977DOI 10.1101/GAD.228544.113 Variant Set Distributions Pathogenic Proximity Analysis Mapped Variants
General Structure Information 2c47 CSNK1G2 structure of casein kinase 1 gamma 2 2.4Å AUTH G.BUNKOCZI,P.RELLOS,S.DAS,E.UGOCHUKWU,O.FEDOROV,F.SOBOTT,AUTH 2 J.ESWARAN,A.AMOS,L.BALL,F.VON DELFT,A.BULLOCK,J.DEBRECZENI,AUTH 3 A.TURNBULL,M.SUNDSTROM,J.WEIGELT,C.ARROWSMITH,A.EDWARDS,AUTH 4 S.KNAPPTITL THE STRUCTURE OF CASEIN KINASE 1 GAMMA 2REF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 2jdr AKT2 structure of pkb-beta (akt2) complexed with the inhibitor a- 443654 2.3Å AUTH T.G.DAVIES,M.L.VERDONK,B.GRAHAM,S.SAALAU-BETHELL,AUTH 2 C.C.F.HAMLETT,T.MCHARDY,I.COLLINS,M.D.GARRETT,AUTH 3 P.WORKMAN,S.J.WOODHEAD,H.JHOTI,D.BARFORDTITL A STRUCTURAL COMPARISON OF INHIBITOR BINDING TOTITL 2 PKB, PKA AND PKA-PKB CHIMERAREF J.MOL.BIOL. V. 367 882 2007REFN ISSN 0022-2836PMID 17275837DOI 10.1016/J.JMB.2007.01.004 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped […]
General Structure Information 4dg6 LRP6 crystal structure of domains 1 and 2 of lrp6 2.9Å AUTH G.HOLDSWORTH,P.SLOCOMBE,C.DOYLE,B.SWEENEY,V.VEVERKA,AUTH 2 K.LE RICH,R.J.FRANKLIN,D.BROOKINGS,J.TURNER,J.KENNEDY,AUTH 3 R.GARLISH,J.SHI,L.NEWNHAM,D.MCMILLAN,M.MUZYLAK,M.CARR,AUTH 4 A.J.HENRY,T.CESKA,M.K.ROBINSONTITL CHARACTERIZATION OF THE INTERACTION OF SCLEROSTIN WITH THETITL 2 LRP FAMILY OF WNT CO-RECEPTORSREF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped […]