General Structure Information
| PDB ID | 2c47 |
| HGNC Gene Label(s) | CSNK1G2 |
| Structure Name | structure of casein kinase 1 gamma 2 |
| Resolution | 2.4Å |
| Reference | AUTH G.BUNKOCZI,P.RELLOS,S.DAS,E.UGOCHUKWU,O.FEDOROV,F.SOBOTT,AUTH 2 J.ESWARAN,A.AMOS,L.BALL,F.VON DELFT,A.BULLOCK,J.DEBRECZENI,AUTH 3 A.TURNBULL,M.SUNDSTROM,J.WEIGELT,C.ARROWSMITH,A.EDWARDS,AUTH 4 S.KNAPPTITL THE STRUCTURE OF CASEIN KINASE 1 GAMMA 2REF TO BE PUBLISHEDREFN |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 289 |
| Number Of SNVs | 41 |
| Number Of Permutations | 4764 |
| Optimal Distance Threshold | 14.0 |
| K Statistic | 0.102 |
| p-value | 0.014 |
COSMIC
| Number Of Residues | 289 |
| Number Of SNVs | 4 |
| Number Of Permutations | 194 |
| Optimal Distance Threshold | 25.0 |
| K Statistic | 0.833 |
| p-value | 0.655 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 41 |
| Number Of COSMIC SNVs | 4 |
| Optimal Distance Threshold | 26.0 |
| K Statistic | 0.517 |
| p-value | 0.754 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
