General Structure Information 2ja3 CLCN5 cytoplasmic domain of the human chloride transporter clc-5 in complex with adp 3.05Å AUTH S.MEYER,S.SAVARESI,I.C.FORSTER,R.DUTZLERTITL NUCLEOTIDE RECOGNITION BY THE CYTOPLASMIC DOMAINTITL 2 OF THE HUMAN CHLORIDE TRANSPORTER CLC-5REF NAT.STRUCT.MOL.BIOL. V. 14 60 2006REFN ISSN 1545-9993PMID 17195847DOI 10.1038/NSMB1188 Variant Set Distributions Mapped Variants
General Structure Information 2ebv NUP153 solution structure of the third zf-ranbp domain from human nuclear pore complex protein nup153 -1.0Å AUTH H.P.ZHANG,F.HAYASHI,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE THIRD ZF-RANBP DOMAINTITL 2 FROM HUMAN NUCLEAR PORE COMPLEX PROTEIN NUP153REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 4bkt VHL von hippel lindau protein:elonginb:elonginc complex, in complex with (2s,4r)-n-methyl-1-[2-(3-methyl-1,2-oxazol-5-yl)ethanoyl]-4- oxidanyl-pyrrolidine-2-carboxamide 2.35Å AUTH D.M.DIAS,I.VAN MOLLE,M.G.J.BAUD,C.GALDEANO,C.F.G.C.GERALDES,AUTH 2 A.CIULLITITL IS NMR FRAGMENT SCREENING FINE-TUNED TO ASSESS DRUGGABILITYTITL 2 OF PROTEIN-PROTEIN INTERACTIONS?REF ACS MED.CHEM.LETT. V. 5 23 2014REFN ISSN 1948-5875PMID 24436777DOI 10.1021/ML400296C Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity […]
General Structure Information 3ua8 GRIA2 crystal structure analysis of a 6-amino quinazolinedione sulfonamide bound to human glur2 1.9Å AUTH D.ORAIN,S.OFNER,M.KOLLER,D.A.CARCACHE,W.FROESTL,H.ALLGEIER,AUTH 2 V.RASETTI,J.NOZULAK,H.MATTES,N.SOLDERMANN,P.FLOERSHEIM,AUTH 3 S.DESRAYAUD,J.KALLEN,K.LINGENHOEHL,S.URWYLERTITL 6-AMINO QUINAZOLINEDIONE SULFONAMIDES AS ORALLY ACTIVETITL 2 COMPETITIVE AMPA RECEPTOR ANTAGONISTS.REF BIOORG.MED.CHEM.LETT. V. 22 996 2012REFN ISSN 0960-894XPMID 22197388DOI 10.1016/J.BMCL.2011.12.009 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic […]
General Structure Information 1k5g RANBP1 crystal structure of ran-gdp-alfx-ranbp1-rangap complex 3.1Å AUTH M.J.SEEWALD,C.KORNER,A.WITTINGHOFER,I.R.VETTERTITL RANGAP MEDIATES GTP HYDROLYSIS WITHOUT AN ARGININETITL 2 FINGER.REF NATURE V. 415 662 2002REFN ISSN 0028-0836PMID 11832950DOI 10.1038/415662A Variant Set Distributions Mapped Variants
General Structure Information 1efv ETFB three-dimensional structure of human electron transfer flavoprotein to 2.1 a resolution 2.1Å AUTH D.L.ROBERTS,F.E.FRERMAN,J.J.KIMTITL THREE-DIMENSIONAL STRUCTURE OF HUMAN ELECTRONTITL 2 TRANSFER FLAVOPROTEIN TO 2.1-A RESOLUTION.REF PROC.NATL.ACAD.SCI.USA V. 93 14355 1996REFN ISSN 0027-8424PMID 8962055DOI 10.1073/PNAS.93.25.14355 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 3fmp NUP214 crystal structure of the nucleoporin nup214 in complex with the dead- box helicase ddx19 3.19Å AUTH J.NAPETSCHNIG,S.A.KASSUBE,E.W.DEBLER,R.W.WONG,G.BLOBEL,AUTH 2 A.HOELZTITL STRUCTURAL AND FUNCTIONAL ANALYSIS OF THE INTERACTIONTITL 2 BETWEEN THE NUCLEOPORIN NUP214 AND THE DEAD-BOX HELICASETITL 3 DDX19.REF PROC.NATL.ACAD.SCI.USA V. 106 3089 2009REFN ISSN 0027-8424PMID 19208808DOI 10.1073/PNAS.0813267106 Variant Set Distributions Ripley’s […]
General Structure Information 2rop ATP7B solution structure of domains 3 and 4 of human atp7b -1.0Å AUTH L.BANCI,I.BERTINI,F.CANTINI,A.C.ROSENZWEIG,AUTH 2 L.A.YATSUNYKTITL METAL BINDING DOMAINS 3 AND 4 OF THE WILSONTITL 2 DISEASE PROTEIN: SOLUTION STRUCTURE ANDTITL 3 INTERACTION WITH THE COPPER(I) CHAPERONE HAH1REF BIOCHEMISTRY V. 47 7423 2008REFN ISSN 0006-2960PMID 18558714DOI 10.1021/BI8004736 Variant Set Distributions Mapped […]
General Structure Information 4ib4 HTR2B crystal structure of the chimeric protein of 5-ht2b-bril in complex with ergotamine 2.7Å AUTH D.WACKER,C.WANG,V.KATRITCH,G.W.HAN,X.P.HUANG,E.VARDY,AUTH 2 J.D.MCCORVY,Y.JIANG,M.CHU,F.Y.SIU,W.LIU,H.E.XU,V.CHEREZOV,AUTH 3 B.L.ROTH,R.C.STEVENSTITL STRUCTURAL FEATURES FOR FUNCTIONAL SELECTIVITY AT SEROTONINTITL 2 RECEPTORS.REF SCIENCE V. 340 615 2013REFN ISSN 0036-8075PMID 23519215DOI 10.1126/SCIENCE.1232808 Variant Set Distributions Mapped Variants
General Structure Information 2koy ATP7B structure of the e1064a mutant of the n-domain of wilson disease associated protein -1.0Å AUTH O.Y.DMITRIEV,S.L.LUTSENKO,E.E.UHLEMANNTITL THE STRUCTURE OF THE E1064A MUTANT REVEALS ATP-DEPENDENTTITL 2 CONFORMATIONAL CHANGES IN THE ATP7B N-DOMAIN.REF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped Variants