General Structure Information
| PDB ID | 3fmp |
| HGNC Gene Label(s) | NUP214 |
| Structure Name | crystal structure of the nucleoporin nup214 in complex with the dead- box helicase ddx19 |
| Resolution | 3.19Å |
| Reference | AUTH J.NAPETSCHNIG,S.A.KASSUBE,E.W.DEBLER,R.W.WONG,G.BLOBEL,AUTH 2 A.HOELZTITL STRUCTURAL AND FUNCTIONAL ANALYSIS OF THE INTERACTIONTITL 2 BETWEEN THE NUCLEOPORIN NUP214 AND THE DEAD-BOX HELICASETITL 3 DDX19.REF PROC.NATL.ACAD.SCI.USA V. 106 3089 2009REFN ISSN 0027-8424PMID 19208808DOI 10.1073/PNAS.0813267106 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 420 |
| Number Of SNVs | 105 |
| Number Of Permutations | 13396 |
| Optimal Distance Threshold | 10.0 |
| K Statistic | 0.047 |
| p-value | 0.35 |
COSMIC
| Number Of Residues | 420 |
| Number Of SNVs | 3 |
| Number Of Permutations | 162 |
| Optimal Distance Threshold | 17.0 |
| K Statistic | 0.667 |
| p-value | 0.174 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 105 |
| Number Of COSMIC SNVs | 3 |
| Optimal Distance Threshold | 17.0 |
| K Statistic | 0.478 |
| p-value | 0.251 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
