Assessment of Structural Intolerance and Durability
General Structure Information 2m16 PSIP1 p75/ledgf pwwp domain -1.0Å AUTH J.O.EIDAHL,B.L.CROWE,J.A.NORTH,C.J.MCKEE,N.SHKRIABAI,L.FENG,AUTH 2 M.PLUMB,R.L.GRAHAM,R.J.GORELICK,S.HESS,M.G.POIRIER,AUTH 3 M.P.FOSTER,M.KVARATSKHELIATITL STRUCTURAL BASIS FOR HIGH-AFFINITY BINDING OF LEDGF PWWP TOTITL 2 MONONUCLEOSOMES.REF NUCLEIC ACIDS RES. V. 41 3924 2013REFN ISSN 0305-1048PMID 23396443DOI 10.1093/NAR/GKT074 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped Variants
General Structure Information 2kdp SAP30 solution structure of the sap30 zinc finger motif -1.0Å AUTH Y.HE,R.IMHOFF,A.SAHU,I.RADHAKRISHNANTITL SOLUTION STRUCTURE OF A NOVEL ZINC FINGER MOTIF INTITL 2 THE SAP30 POLYPEPTIDE OF THE SIN3 COREPRESSORTITL 3 COMPLEX AND ITS POTENTIAL ROLE IN NUCLEIC ACIDTITL 4 RECOGNITIONREF NUCLEIC ACIDS RES. V. 37 2142 2009REFN ISSN 0305-1048PMID 19223330DOI 10.1093/NAR/GKP051 […]
General Structure Information 1uzc PRPF40A the structure of an ff domain from human hypa/fbp11 -1.0Å AUTH M.D.ALLEN,A.FRIEDLER,O.SCHON,M.BYCROFTTITL THE STRUCTURE OF AN FF DOMAIN FROM HUMANTITL 2 HYPA/FBP11.REF J.MOL.BIOL. V. 323 411 2002REFN ISSN 0022-2836PMID 12381297DOI 10.1016/S0022-2836(02)00968-3 Variant Set Distributions Mapped Variants
General Structure Information 2ivx CCNT2 crystal structure of human cyclin t2 at 1.8 a resolution (casp target) 1.8Å AUTH S.BAUMLI,G.LOLLI,E.D.LOWE,S.TROIANI,L.RUSCONI,A.N.BULLOCK,AUTH 2 J.E.DEBRECZENI,S.KNAPP,L.N.JOHNSONTITL THE STRUCTURE OF P-TEFB (CDK9/CYCLIN T1), ITS COMPLEX WITHTITL 2 FLAVOPIRIDOL AND REGULATION BY PHOSPHORYLATION.REF EMBO J. V. 27 1907 2008REFN ISSN 0261-4189PMID 18566585DOI 10.1038/EMBOJ.2008.121 Variant Set Distributions Mapped Variants
General Structure Information 2cs8 ST18 solution structure of tandem repeat of the fifth and sixth zinc-finger c2hc domains from human st18 -1.0Å AUTH T.SUETAKE,T.NAGASHIMA,F.HAYASHI,S.YOKOYAMATITL SOLUTION STRUCTURE OF TANDEM REPEAT OF THE FIFTHTITL 2 AND SIXTH ZINC-FINGER C2HC DOMAINS FROM HUMAN ST18REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 3qve HBP1 crystal structure of human hmg box-containing protein 1, hbp1 2.04Å AUTH A.CHAIKUAD,E.KRYSZTOFINSKA,R.COCKING,M.VOLLMAR,W.W.YUE,AUTH 2 T.KROJER,E.UGOCHUKWU,P.FILIPPAKOPOULOS,F.VON DELFT,AUTH 3 C.H.ARROWSMITH,J.WEIGELT,A.M.EDWARDS,C.BOUNTRA,U.OPPERMANN,AUTH 4 STRUCTURAL GENOMICS CONSORTIUMTITL CRYSTAL STRUCTURE OF HUMAN HMG BOX-CONTAINING PROTEIN 1,TITL 2 HBP1REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2rpc ZIC3 solution structure of the tandem zf-c2h2 domains from the human zinc finger protein zic 3 -1.0Å AUTH M.HATAYAMA,T.TOMIZAWA,K.SAKAI-KATO,P.BOUVAGNET,AUTH 2 S.KOSE,N.IMAMOTO,S.YOKOYAMA,N.UTSUNOMIYA-TATE,AUTH 3 K.MIKOSHIBA,T.KIGAWA,J.ARUGATITL FUNCTIONAL AND STRUCTURAL BASIS OF THE NUCLEARTITL 2 LOCALIZATION SIGNAL IN THE ZIC3 ZINC FINGER DOMAINREF HUM.MOL.GENET. V. 17 3459 2008REFN ISSN 0964-6906PMID 18716025DOI 10.1093/HMG/DDN239 Variant Set Distributions […]
General Structure Information 2cq0 EIF3G solution structure of rna binding domain in eukaryotic translation initiation factor 3 subunit 4 -1.0Å AUTH K.TSUDA,Y.MUTO,M.INOUE,T.KIGAWA,T.TERADA,AUTH 2 M.SHIROUZU,S.YOKOYAMATITL SOLUTION STRUCTURE OF RNA BINDING DOMAIN INTITL 2 EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNITTITL 3 4REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 3l6y CTNND1 crystal structure of p120 catenin in complex with e-cadherin 3.0Å AUTH N.ISHIYAMA,S.H.LEE,S.LIU,G.Y.LI,M.J.SMITH,L.F.REICHARDT,AUTH 2 M.IKURATITL DYNAMIC AND STATIC INTERACTIONS BETWEEN P120 CATENIN ANDTITL 2 E-CADHERIN REGULATE THE STABILITY OF CELL-CELL ADHESION.REF CELL(CAMBRIDGE,MASS.) V. 141 117 2010REFN ISSN 0092-8674PMID 20371349DOI 10.1016/J.CELL.2010.01.017 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic […]
General Structure Information 3k27 EED complex structure of eed and trimethylated h3k9 1.76Å AUTH C.XU,C.BIAN,W.YANG,M.GALKA,H.OUYANG,C.CHEN,W.QIU,H.LIU,AUTH 2 A.E.JONES,F.MACKENZIE,P.PAN,S.S.LI,H.WANG,J.MINTITL BINDING OF DIFFERENT HISTONE MARKS DIFFERENTIALLY REGULATESTITL 2 THE ACTIVITY AND SPECIFICITY OF POLYCOMB REPRESSIVE COMPLEXTITL 3 2 (PRC2).REF PROC.NATL.ACAD.SCI.USA V. 107 19266 2010REFN ISSN 0027-8424PMID 20974918DOI 10.1073/PNAS.1008937107 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons […]