General Structure Information
| PDB ID | 3k27 |
| HGNC Gene Label(s) | EED |
| Structure Name | complex structure of eed and trimethylated h3k9 |
| Resolution | 1.76Å |
| Reference | AUTH C.XU,C.BIAN,W.YANG,M.GALKA,H.OUYANG,C.CHEN,W.QIU,H.LIU,AUTH 2 A.E.JONES,F.MACKENZIE,P.PAN,S.S.LI,H.WANG,J.MINTITL BINDING OF DIFFERENT HISTONE MARKS DIFFERENTIALLY REGULATESTITL 2 THE ACTIVITY AND SPECIFICITY OF POLYCOMB REPRESSIVE COMPLEXTITL 3 2 (PRC2).REF PROC.NATL.ACAD.SCI.USA V. 107 19266 2010REFN ISSN 0027-8424PMID 20974918DOI 10.1073/PNAS.1008937107 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 360 |
| Number Of SNVs | 30 |
| Number Of Permutations | 4758 |
| Optimal Distance Threshold | 11.0 |
| K Statistic | 0.046 |
| p-value | 0.13 |
COSMIC
| Number Of Residues | 360 |
| Number Of SNVs | 5 |
| Number Of Permutations | 72 |
| Optimal Distance Threshold | 18.0 |
| K Statistic | 0.1 |
| p-value | 0.619 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 30 |
| Number Of COSMIC SNVs | 5 |
| Optimal Distance Threshold | 24.0 |
| K Statistic | 0.346 |
| p-value | 0.627 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
