General Structure Information
| PDB ID | 3l6y |
| HGNC Gene Label(s) | CTNND1 |
| Structure Name | crystal structure of p120 catenin in complex with e-cadherin |
| Resolution | 3.0Å |
| Reference | AUTH N.ISHIYAMA,S.H.LEE,S.LIU,G.Y.LI,M.J.SMITH,L.F.REICHARDT,AUTH 2 M.IKURATITL DYNAMIC AND STATIC INTERACTIONS BETWEEN P120 CATENIN ANDTITL 2 E-CADHERIN REGULATE THE STABILITY OF CELL-CELL ADHESION.REF CELL(CAMBRIDGE,MASS.) V. 141 117 2010REFN ISSN 0092-8674PMID 20371349DOI 10.1016/J.CELL.2010.01.017 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 376 |
| Number Of SNVs | 74 |
| Number Of Permutations | 27073 |
| Optimal Distance Threshold | 20.0 |
| K Statistic | 0.219 |
| p-value | 0.024 |
COSMIC
| Number Of Residues | 376 |
| Number Of SNVs | 8 |
| Number Of Permutations | 4499 |
| Optimal Distance Threshold | 34.0 |
| K Statistic | 0.357 |
| p-value | 0.138 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 74 |
| Number Of COSMIC SNVs | 5 |
| Optimal Distance Threshold | 44.0 |
| K Statistic | -0.399 |
| p-value | 0.028 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
